Petrozzi J W, Barton J O, Kligman A, de los Reyes O
Arch Dermatol. 1979 Apr;115(4):436-9.
Analysis of standard fluorescent sunlamps (Westinghouse) indicates that in addition to UVB (290 to 320 nm), a considerable amount of UVA (320 to 400 nm) is also present in their emissions. Since the benefits of topical psoralen administration and UVA have already been demonstrated, and prior experience by ourselves and others with UVB has indicated that some psoriasis benefited from UVB alone, localized areas and plaques of 20 patients were treated with topical administration of psoralens and fluorescent sunlamp bulbs to determine if such a light source with this emission spectrum would be advantageous. Results indicated a total resolution in 17 of 20 patients after an average of 18 treatments. Adverse blistering phototoxic reactions and excessive hyperpigmentation were not encountered. The UVB erythema response of normal skin served as the guide to light dosage in the same manner as administration of the Goeckerman regimen. Therefore, the use of psoralens was very effective when combined with fluorescent sunlamp irradiation; however, the potential risks of photocarcinogenicity makes this treatment experimental and should be reserved for recalcitrant cases.
对标准荧光太阳灯（西屋公司）的分析表明，除了中波紫外线（290至320纳米）外，其发射中还存在相当数量的长波紫外线（320至400纳米）。由于外用补骨脂素和长波紫外线的益处已得到证实，而且我们自己以及其他人先前使用中波紫外线的经验表明，一些银屑病患者仅从中波紫外线治疗中获益，因此对20例患者的局部区域和斑块采用外用补骨脂素和荧光太阳灯泡进行治疗，以确定这种具有该发射光谱的光源是否具有优势。结果显示，平均18次治疗后，20例患者中有17例完全治愈。未出现不良的水疱性光毒性反应和过度色素沉着。正常皮肤的中波紫外线红斑反应与戈克曼疗法给药时一样，作为光剂量的指导。因此，补骨脂素与荧光太阳灯照射联合使用时非常有效；然而，光致癌的潜在风险使得这种治疗具有实验性，应仅用于顽固性病例。
