病毒和细菌呼吸道感染与幼儿哮喘患儿喘息加重的关联。
The association of viral and bacterial respiratory infections with exacerbations of wheezing in young asthmatic children.
作者信息
McIntosh K, Ellis E F, Hoffman L S, Lybass T G, Eller J J, Fulginiti V A
出版信息
J Pediatr. 1973 Apr;82(4):578-90. doi: 10.1016/s0022-3476(73)80582-7.
Abstract
The relationship between exacerbations of wheezing and infection of the respiratory tract was studied prospectively in 32 young hospitalized asthmatic children. Of 139 episodes of wheezing, 58 (42 per cent) were associated with identifiable viral infections. There were 25 respiratory syncytial virus infections; wheezing occurred in 24 of these and pneumonia in 13. Parainfluenza type 2 infection appeared to be next most likely to be associated with wheezing, followed by coronavirus infection. Influenza A. (Hong Kong) was not associated with wheezing in any of the children. Infection with “pathogenic” bacteria was not statistically associated with wheezing.
摘要
对32名住院的哮喘患儿进行了前瞻性研究，以探讨喘息加重与呼吸道感染之间的关系。在139次喘息发作中，58次（42%）与可识别的病毒感染有关。其中有25次呼吸道合胞病毒感染；其中24次出现喘息，13次出现肺炎。2型副流感病毒感染似乎是其次最有可能与喘息相关的，其次是冠状病毒感染。甲型流感（香港）在任何患儿中均未与喘息相关。“致病性”细菌感染与喘息在统计学上无关联。
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