钙离子刺激的核糖核酸酶。大鼠乳腺分化组织的一种新的标记酶。
Ca2+-stimulated ribonuclease. A new marker enzyme of differentiated rat mammary tissues.
作者信息
Liu D K, Kulick D, Williams G H
出版信息
Biochem J. 1979 Jan 15;178(1):241-4. doi: 10.1042/bj1780241.
Abstract
A unique ribonuclease, active only in the presence of Ca2+, was present in lactating mammary gland and milk of the rat. This enzyme was absent from virgin-rat mammary gland and non-mammary tissues of lactating rats. The presence of moderate activity in differentiated mammary tumours, together with an increase in activity in normal tissue parelleling development of mammary function, identify this enzyme as a marker of mammary differentiation in the rat.
摘要
一种独特的核糖核酸酶仅在Ca2+存在时具有活性，它存在于大鼠的泌乳乳腺和乳汁中。这种酶在未成熟大鼠的乳腺以及泌乳大鼠的非乳腺组织中不存在。在分化的乳腺肿瘤中存在适度活性，以及正常组织中的活性随着乳腺功能的发育而增加，这表明这种酶是大鼠乳腺分化的一个标志物。
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本文引用的文献
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BIOCHEMICAL AND MORPHOLOGIC PROPERTIES OF A NEW LACTATING MAMMARY TUMOR LINE IN THE RAT.大鼠一种新的泌乳期乳腺肿瘤细胞系的生化及形态学特性
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Ribonucleases.核糖核酸酶
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Alkaline ribonuclease and ribonuclease inhibitor in mammary gland during the lactation cycle and in the R3230AC mammary tumour.泌乳周期中以及在R3230AC乳腺肿瘤中的乳腺碱性核糖核酸酶和核糖核酸酶抑制剂
Biochem J. 1975 Apr;148(1):67-76. doi: 10.1042/bj1480067.
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Ca2+-stimulated ribonucleases from rat mammary gland and R3230AC mammary adenocarcinoma nuclei.来自大鼠乳腺和R3230AC乳腺腺癌细胞核的钙离子刺激核糖核酸酶
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Biochem J. 1977 May 15;164(2):371-7. doi: 10.1042/bj1640371.
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