人类肾母细胞瘤中的一种肿瘤相关抗原。
A tumor-associated antigen in human nephroblastomas.
作者信息
Burtin P, Gendron M C
出版信息
Proc Natl Acad Sci U S A. 1973 Jul;70(7):2051-4. doi: 10.1073/pnas.70.7.2051.
Abstract
Antisera prepared against extracts of human nephroblastomas (Wilms' tumors) allowed the characterization in these extracts, and in a few extracts of tumors of other organs, of a tumor-associated antigen. This antigen is different from all previously described antigens, and was named W antigen (W for Wilms). It does not seem to be a carcinoembryonic antigen, and hence it could be of viral origin.
摘要
用人类肾母细胞瘤（威尔姆斯瘤）提取物制备的抗血清，使得在这些提取物以及其他一些器官肿瘤的提取物中，鉴定出一种肿瘤相关抗原成为可能。这种抗原不同于之前描述的所有抗原，被命名为W抗原（W代表威尔姆斯）。它似乎不是癌胚抗原，因此可能起源于病毒。
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