Kumar S, Carr T, Marsden H B, Morris-Jones P H
J Clin Pathol. 1986 Jul;39(7):736-41. doi: 10.1136/jcp.39.7.736.
Six peroxidase conjugated lectins were used to compare their ability to bind to formalin fixed paraffin embedded tissue sections of childhood renal tumours (Wilms' tumour, mesoblastic nephroma, renal carcinoma, rhabdoid renal tumour, and bone metastasising renal tumour of childhood (BMRTC) with fetal and normal children's kidney. Lectins were found to be helpful in the differential diagnosis of renal tumours. Another important finding was that the mesenchyme of renal tumours showed differences in its reactivity among various types of kidney tumours. The results of lectin binding were not helpful in establishing the origin of kidney tumours.
使用六种过氧化物酶偶联凝集素，比较它们与儿童肾肿瘤（肾母细胞瘤、中胚叶肾瘤、肾癌、横纹肌样肾肿瘤以及儿童骨转移性肾肿瘤（BMRTC））的福尔马林固定石蜡包埋组织切片以及胎儿和正常儿童肾脏的结合能力。发现凝集素有助于肾肿瘤的鉴别诊断。另一个重要发现是，肾肿瘤的间充质在不同类型的肾肿瘤中表现出反应性差异。凝集素结合结果对确定肾肿瘤的起源并无帮助。
