α-二氟甲基鸟氨酸耗尽细胞内的腐胺和亚精胺并不抑制9L大鼠脑肿瘤细胞的增殖。 - Suppr

Suppr

超能文献

Depletion of intracellular putrescine and spermidine by alpha-difluromethylornithine does not inhibit proliferation of 9L rat brain tumor cells.

作者信息

Seidenfeld J, Marton L J

出版信息

Biochem Biophys Res Commun. 1979 Feb 28;86(4):1192-8. doi: 10.1016/0006-291x(79)90243-2.

DOI:10.1016/0006-291x(79)90243-2

PMID:435319

Abstract

摘要

相似文献

Depletion of intracellular putrescine and spermidine by alpha-difluromethylornithine does not inhibit proliferation of 9L rat brain tumor cells.α-二氟甲基鸟氨酸耗尽细胞内的腐胺和亚精胺并不抑制9L大鼠脑肿瘤细胞的增殖。

Biochem Biophys Res Commun. 1979 Feb 28;86(4):1192-8. doi: 10.1016/0006-291x(79)90243-2.

Effects of DL-alpha-methylornithine on proliferation and polyamine content of 9L rat brain tumor cells.DL-α-甲基鸟氨酸对9L大鼠脑肿瘤细胞增殖和多胺含量的影响。

Cancer Res. 1980 Jun;40(6):1961-6.

Role of polyamines in the proliferation and steroidogenic activities of bovine adrenocortical cells in culture.多胺在体外培养的牛肾上腺皮质细胞增殖和类固醇生成活性中的作用

Biochem Biophys Res Commun. 1981 Dec 31;103(4):1294-301. doi: 10.1016/0006-291x(81)90263-1.

Effect of alpha-difluoromethylornithine, an enzyme-activated irreversible inhibitor of ornithine decarboxylase, on polyamine levels in rat tissues.α-二氟甲基鸟氨酸（一种鸟氨酸脱羧酶的酶激活不可逆抑制剂）对大鼠组织中多胺水平的影响。

Life Sci. 1979 Feb 5;24(6):519-24. doi: 10.1016/0024-3205(79)90173-5.

Anti-proliferative properties of DL-alpha-difluoromethyl ornithine in cultured cells. A consequence of the irreversible inhibition of ornithine decarboxylase.DL-α-二氟甲基鸟氨酸在培养细胞中的抗增殖特性。鸟氨酸脱羧酶不可逆抑制的结果。

Biochem Biophys Res Commun. 1978 Mar 15;81(1):58-66. doi: 10.1016/0006-291x(78)91630-3.

Depletion of 9L rat brain tumor cell polyamine content by treatment with D,L-alpha-difluoromethylornithine inhibits proliferation and the G1 to S transition.用D，L-α-二氟甲基鸟氨酸处理使9L大鼠脑肿瘤细胞的多胺含量耗竭，可抑制细胞增殖及G1期到S期的转变。

Exp Cell Res. 1981 Jan;131(1):209-16. doi: 10.1016/0014-4827(81)90420-1.

Irreversible inhibition of the early increase in ornithine decarboxylase activity following growth stimulation is required to block Ehrlich ascites tumor cell proliferation in culture.要阻断培养中的艾氏腹水癌细胞增殖，需要对生长刺激后鸟氨酸脱羧酶活性的早期增加进行不可逆抑制。

Biochem Biophys Res Commun. 1980 May 14;94(1):151-8. doi: 10.1016/s0006-291x(80)80200-2.

Ornithine decarboxylase activity and polyamines in relation to aging of human fibroblasts.鸟氨酸脱羧酶活性和多胺与人类成纤维细胞衰老的关系

Exp Cell Res. 1977 Sep;108(2):435-40. doi: 10.1016/s0014-4827(77)80052-9.

Ovarian function in the rat following irreversible inhibition of L-ornithine decarboxylase.L-鸟氨酸脱羧酶不可逆抑制后大鼠的卵巢功能

Life Sci. 1980 Dec 8;27(23):2277-83. doi: 10.1016/0024-3205(80)90395-1.

Polyamines in brain and heart of the neonatal rat: effects of inhibitors of ornithine decarboxylase and spermidine synthase.新生大鼠脑和心脏中的多胺：鸟氨酸脱羧酶和亚精胺合酶抑制剂的作用。

Life Sci. 1984 Sep 3;35(10):1125-31. doi: 10.1016/0024-3205(84)90078-x.

引用本文的文献

Effects of inhibitors of spermidine and spermine synthesis on polyamine concentrations and growth of transformed mouse fibroblasts.亚精胺和精胺合成抑制剂对转化小鼠成纤维细胞多胺浓度及生长的影响

Biochem J. 1981 Jan 15;194(1):79-89. doi: 10.1042/bj1940079.

Specificity of mammalian spermidine synthase and spermine synthase.哺乳动物亚精胺合酶和精胺合酶的特异性

Biochem J. 1981 Aug 1;197(2):315-20. doi: 10.1042/bj1970315.

Spermine binding to submitochondrial particles and activation of adenosine triphosphatase.精胺与亚线粒体颗粒的结合及三磷酸腺苷酶的激活。

Biochem J. 1984 Mar 1;218(2):495-9. doi: 10.1042/bj2180495.

Regulation of spermidine/spermine N1-acetyltransferase in L6 cells by polyamines and related compounds.多胺及相关化合物对L6细胞中精胺/亚精胺N1-乙酰基转移酶的调控

Biochem J. 1986 Sep 1;238(2):581-7. doi: 10.1042/bj2380581.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验