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人生长激素治疗对儿童脂肪组织的影响。

Effect of human growth hormone treatment on adipose tissue in children.

作者信息

Brook C G

出版信息

Arch Dis Child. 1973 Sep;48(9):725-8. doi: 10.1136/adc.48.9.725.

DOI:10.1136/adc.48.9.725
PMID:4354780
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1648493/
Abstract

Body fat and the size and number of adipose cells were determined in 22 children with growth hormone deficiency before and after 6 months of replacement therapy with human growth hormone (HGH). A marked reduction in body fat and adipose cell size was found, and the total number of adipose cells increased at the normal rate during treatment. HGH does not appear to induce catch-up growth in the number of adipose cells.

摘要

对22名生长激素缺乏儿童在接受人生长激素（HGH）替代治疗6个月前后的体脂、脂肪细胞大小和数量进行了测定。结果发现，体脂和脂肪细胞大小显著降低，且治疗期间脂肪细胞总数以正常速率增加。HGH似乎并未诱导脂肪细胞数量的追赶性生长。

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Effect of human growth hormone treatment on adipose tissue in children.人生长激素治疗对儿童脂肪组织的影响。
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2
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引用本文的文献

1
Longitudinal anthropometric measurements in patients with growth hormone deficiency. Effect of human growth hormone treatment.生长激素缺乏症患者的纵向人体测量。人生长激素治疗的效果。
Eur J Pediatr. 1982 Feb;138(1):38-45. doi: 10.1007/BF00442326.
2
The effect of human growth hormone therapy on skinfold thickness in growth hormone-deficient children.生长激素治疗对生长激素缺乏儿童皮褶厚度的影响。
Eur J Pediatr. 1988 Aug;147(6):588-92. doi: 10.1007/BF00442469.

本文引用的文献

1
Concepts relating the pituitary growth hormone to somatic growth of the normal child.与垂体生长激素相关的正常儿童身体生长的概念。
AMA J Dis Child. 1960 Mar;99:349-79. doi: 10.1001/archpedi.1960.02070030351012.
2
Design and accuracy of calipers for measuring subcutaneous tissue thickness.用于测量皮下组织厚度的卡尺的设计与准确性。
Br J Nutr. 1955;9(2):133-43. doi: 10.1079/bjn19550021.
3
AN EVALUATION OF SEVENTY-FIVE PATIENTS WITH HYPOPITUITARISM BEGINNING IN CHILDHOOD.
Am J Med. 1965 Apr;38:484-98. doi: 10.1016/0002-9343(65)90127-0.
4
Effect of growth hormone on plasma fatty acids.生长激素对血浆脂肪酸的影响。
J Clin Invest. 1959 Mar;38(3):484-8. doi: 10.1172/JCI103824.
5
The effect of human growth hormone on subcutaneous fat thickness in hyposomatotrophic and panhypopituitary dwarfs.人生长激素对生长激素缺乏型和全垂体功能减退型侏儒症患者皮下脂肪厚度的影响。
J Endocrinol. 1967 Oct;39(2):263-75. doi: 10.1677/joe.0.0390263.
6
The assessment of the amount of fat in the human body from measurements of skinfold thickness.通过测量皮褶厚度来评估人体脂肪含量。
Br J Nutr. 1967 Aug;21(3):681-9. doi: 10.1079/bjn19670070.
7
Determination of body composition of children from skinfold measurements.通过皮褶测量确定儿童的身体成分。
Arch Dis Child. 1971 Apr;46(246):182-4. doi: 10.1136/adc.46.246.182.
8
Effect of human growth hormone treatment for 1 to 7 years on growth of 100 children, with growth hormone deficiency, low birthweight, inherited smallness, Turner's syndrome, and other complaints.对100名患有生长激素缺乏症、低出生体重、遗传性身材矮小、特纳综合征及其他病症的儿童进行1至7年生长激素治疗的效果
Arch Dis Child. 1971 Dec;46(250):745-82. doi: 10.1136/adc.46.250.745.
9
Human growth hormone.人生长激素
Nature. 1972 Jun 23;237(5356):433-9. doi: 10.1038/237433a0.
10
Methods for the determination of adipose cell size in man and animals.人类和动物体内脂肪细胞大小的测定方法。
J Lipid Res. 1968 Jan;9(1):110-9.