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1
Independent segregation of the H-2 locus and the locus for responsiveness to histamine-sensitizing factor.H-2基因座与对组胺致敏因子反应性基因座的独立分离。
Proc Natl Acad Sci U S A. 1973 Sep;70(9):2500-1. doi: 10.1073/pnas.70.9.2500.
2
Isolation from Bordetella pertussis of protective antigen free from toxic activity and histamine sensitizing factor.从百日咳博德特氏菌中分离出无毒性活性和组胺致敏因子的保护性抗原。
Nature. 1967 Apr 1;214(5083):96-7. doi: 10.1038/214096a0.
3
Locus controlling Bordetella pertussis-induced histamine sensitization (Bphs), an autoimmune disease-susceptibility gene, maps distal to T-cell receptor beta-chain gene on mouse chromosome 6.控制百日咳博德特氏菌诱导的组胺致敏作用的基因座（Bphs）是一种自身免疫性疾病易感基因，定位于小鼠6号染色体上T细胞受体β链基因的远端。
Proc Natl Acad Sci U S A. 1993 Apr 15;90(8):3700-4. doi: 10.1073/pnas.90.8.3700.
4
Further studies on the inheritance of responsiveness to pertussis HSF in mice.
Int Arch Allergy Appl Immunol. 1975;48(1):11-5. doi: 10.1159/000231288.
5
Acute autoimmune encephalomyelitis in mice. II. Susceptibility is controlled by the combination of H-2 and histamine sensitization genes.小鼠急性自身免疫性脑脊髓炎。II. 易感性由H-2和组胺致敏基因的组合控制。
J Exp Med. 1982 Jul 1;156(1):31-40. doi: 10.1084/jem.156.1.31.
6
Antigens of Bordetella pertussis. IV. Effect of heat, merthiolate, and formaldehyde on histamine-sensitizing factor and protective activity of soluble extracts from Bordetella pertussi.s.百日咳博德特氏菌抗原。IV. 热、硫柳汞和甲醛对百日咳博德特氏菌可溶性提取物的组胺致敏因子和保护活性的影响。
J Bacteriol. 1966 Jun;91(6):2175-9. doi: 10.1128/jb.91.6.2175-2179.1966.
7
[Toxic factors of Bordetella pertussis, with special reference to leukocytosis-promoting factor, histamine-sensitizing factor and hemagglutinins (author's transl)].
Tanpakushitsu Kakusan Koso. 1976 Nov;Suppl:164-83.
8
[Bordetella pertussis spheroplasts. 4. The protective, histamine-sensitizing and toxic action of spheroplasts and spheroplast cell walls].
Zentralbl Bakteriol Orig A. 1972 Mar;219(3):358-65.
9
Histopathological changes in mice treated with extracts of the histamine-sensitizing factor of Bordetella pertussis.用百日咳博德特氏菌组胺致敏因子提取物处理的小鼠的组织病理学变化。
Int Arch Allergy Appl Immunol. 1977;54(2):129-42. doi: 10.1159/000231816.
10
Segregation at a locus determining an immunoglobulin genetic marker for the light chain variable region affects inheritance of expression of an idiotype.决定轻链可变区免疫球蛋白遗传标记的基因座上的分离影响独特型表达的遗传。
Proc Natl Acad Sci U S A. 1977 Oct;74(10):4600-4. doi: 10.1073/pnas.74.10.4600.

引用本文的文献

1
Locus controlling Bordetella pertussis-induced histamine sensitization (Bphs), an autoimmune disease-susceptibility gene, maps distal to T-cell receptor beta-chain gene on mouse chromosome 6.控制百日咳博德特氏菌诱导的组胺致敏作用的基因座（Bphs）是一种自身免疫性疾病易感基因，定位于小鼠6号染色体上T细胞受体β链基因的远端。
Proc Natl Acad Sci U S A. 1993 Apr 15;90(8):3700-4. doi: 10.1073/pnas.90.8.3700.
2
Experimental allergic orchitis in mice. II. Association of disease susceptibility with the locus controlling Bordetella pertussis-induced sensitivity to histamine.小鼠实验性变应性睾丸炎。II. 疾病易感性与控制百日咳博德特氏菌诱导的组胺敏感性的基因座的关联。
Immunogenetics. 1985;22(5):417-25. doi: 10.1007/BF00418088.
3
Experimental allergic orchitis in mice. I. Genetic control of susceptibility and resistance to induction of autoimmune orchitis.小鼠实验性变应性睾丸炎。I. 自身免疫性睾丸炎诱导易感性和抗性的遗传控制
Immunogenetics. 1985;22(4):323-33. doi: 10.1007/BF00430916.
4
Suppression of IgE antibody production in SJL mice. I. Nonspecific suppressor T cells.SJL小鼠中IgE抗体产生的抑制作用。I. 非特异性抑制性T细胞。
J Exp Med. 1976 Apr 1;143(4):833-45. doi: 10.1084/jem.143.4.833.

本文引用的文献

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[Technique of obtaining blood samples from small laboratory animals by puncture of ophthalmic plexus].[通过穿刺眼丛从小型实验动物获取血样的技术]
C R Seances Soc Biol Fil. 1951 Oct;145(19-20):1465-6.
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Method of preparing histamine sensitizing factor.组胺致敏因子的制备方法。
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The antibody response to tumor inoculation; improved methods of antibody detection.对肿瘤接种的抗体反应；改进的抗体检测方法。
Cancer Res. 1954 Oct;14(9):651-5.
4
Genetic control of the antibody response. II. Further analysis of the specificity of determinant-specific control, and genetic analysis of the response to (H,G)-A--L in CBA and C57 mice.抗体应答的遗传控制。II. 决定簇特异性控制特异性的进一步分析，以及CBA和C57小鼠对（H，G）-A--L应答的遗传分析。
J Exp Med. 1967 Nov 1;126(5):969-78. doi: 10.1084/jem.126.5.969.
5
Genetic control of the antibody response. I. Demonstration of determinant-specific differences in response to synthetic polypeptide antigens in two strains of inbred mice.抗体反应的遗传控制。I. 两个近交系小鼠对合成多肽抗原反应中决定簇特异性差异的证明。
J Exp Med. 1965 Sep 1;122(3):517-31. doi: 10.1084/jem.122.3.517.
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The G-IX system. A cell surface allo-antigen associated with murine leukemia virus; implications regarding chromosomal integration of the viral genome.G-IX系统。一种与鼠白血病病毒相关的细胞表面同种异体抗原；关于病毒基因组染色体整合的意义。
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7
H-2-linked genetic control of immune responsiveness to ovalbumin and ovomucoid.与H-2相关的对卵清蛋白和卵类粘蛋白免疫反应性的遗传控制。
J Exp Med. 1971 Nov 1;134(5):1335-48. doi: 10.1084/jem.134.5.1335.
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Genetic control of the immune response. Mapping of the Ir-1 locus.免疫反应的遗传控制。Ir-1基因座的定位。
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9
Inheritance of responsiveness to pertussis HSF in mice.
Int Arch Allergy Appl Immunol. 1970;38(6):573-89. doi: 10.1159/000230313.
10
Histamine-sensitizing factors from microbial agents, with special reference to Bordetella pertussis.来自微生物制剂的组胺致敏因子，特别提及百日咳博德特氏菌。
Bacteriol Rev. 1968 Jun;32(2):103-26. doi: 10.1128/br.32.2.103-126.1968.

H-2基因座与对组胺致敏因子反应性基因座的独立分离。

Independent segregation of the H-2 locus and the locus for responsiveness to histamine-sensitizing factor.

作者信息

Ovary Z, Vris T W, de Szalay C, Vaz N M, Iritani C A

出版信息

Proc Natl Acad Sci U S A. 1973 Sep;70(9):2500-1. doi: 10.1073/pnas.70.9.2500.

DOI:10.1073/pnas.70.9.2500
PMID:4354853
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC427042/
Abstract

The inheritance of responsiveness to histamine-sensitizing factor of pertussis bacilli was examined in (SWR/J x CBA/J)F(1) x CBA/J backcross mice. We found that about half of the backcross mice inherited this responsiveness in both sexes. There was no linkage between the inheritance of responsiveness to histamine-sensitizing factor and the H-2(q) locus from the sensitive SW/J progenitor.

摘要

在（SWR/J×CBA/J）F1×CBA/J回交小鼠中检测了对百日咳杆菌组胺致敏因子反应性的遗传情况。我们发现约一半的回交小鼠在两性中都遗传了这种反应性。对组胺致敏因子反应性的遗传与来自敏感的SWR/J亲本的H-2(q)位点之间没有连锁关系。