Friis C
Biol Neonate. 1979;35(3-4):180-7. doi: 10.1159/000241170.
Glomerular filtration rate (GFR), estimated as clearance of inulin, and clearance of p-aminohippuric acid (CPAH) were measured in 32 unanaesthetized piglets 1--62 days of age. During this period of time, GFR increased from 0.27 to 0.59 ml/min/g kidney and CPAH increased from 1.02 to 1.72 ml/min/g kidney. At 8 weeks of age, GFR and CPAH equaled adult values. In addition, renal PAH extraction (EPAH) was estimated in 12 anaesthetized piglets aged 1--79 days. EPAH increased from 0.75 at birth to 0.86 (adult value) at 3 weeks of age. The result shows a postnatal increase in renal functions in piglets, but the development from birth to adult level was less pronounced than seen in other animal species.
在32只1至62日龄未麻醉的仔猪中测量了以菊粉清除率估算的肾小球滤过率（GFR）和对氨基马尿酸清除率（CPAH）。在此期间，GFR从0.27增加至0.59毫升/分钟/克肾脏，CPAH从1.02增加至1.72毫升/分钟/克肾脏。在8周龄时，GFR和CPAH达到成年值。此外，在12只1至79日龄麻醉仔猪中估算了肾脏对PAH的摄取率（EPAH）。EPAH从出生时的0.75增加至3周龄时的0.86（成年值）。结果表明仔猪出生后肾功能有所增加，但从出生到成年水平的发育不如其他动物物种明显。
