猿猴病毒40诱导的转化对小鼠成纤维细胞转移RNA同功受体种类的影响。
Effects of simian virus 40-induced transformation on isoaccepting species of transfer RNA from mouse fibroblasts.
作者信息
Portugal F H, Simonds J S, Twardzik D, Oskarsson M
出版信息
J Virol. 1973 Dec;12(6):1616-9. doi: 10.1128/JVI.12.6.1616-1619.1973.
Abstract
Alterations in isoaccepting species of tRNA in mouse fibroblasts transformed by simian virus 40 were determined for alanine, arginine, histidine, leucine, lysine, phenylalanine, serine, tyrosine, and valine. Significant differences between transformed cells in culture and newborn mouse cells are attributed to tRNA alterations accompanying differentiation of mouse cells.
摘要
测定了经猴病毒40转化的小鼠成纤维细胞中丙氨酸、精氨酸、组氨酸、亮氨酸、赖氨酸、苯丙氨酸、丝氨酸、酪氨酸和缬氨酸的同功受体tRNA种类的变化。培养的转化细胞与新生小鼠细胞之间的显著差异归因于小鼠细胞分化过程中伴随的tRNA变化。
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