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视网膜敏感性的控制。II. 外网状层的侧向相互作用。

Control of retinal sensitivity. II. Lateral interactions at the outer plexi form layer.

作者信息

Werblin F S

出版信息

J Gen Physiol. 1974 Jan;63(1):62-87. doi: 10.1085/jgp.63.1.62.

Abstract

Test stimuli, presented at the center of the bipolar cell receptive field, spanning less than 2 log units of intensity, elicit the full range of graded response. The intensity range of test stimuli that elicits the graded response depends upon the background conditions. A higher range of log test intensities is required to elicit the graded bipolar response in the presence of surround backgrounds. But surround backgrounds can also serve to unsaturate the bipolar response and thereby increase sensitivity under certain conditions. The results suggest that a second stage of sensitivity-control is mediated by the horizontal cell system at the outer plexiform layer, concatenated with the effects of adaptation in the photoreceptors.

摘要

呈现于双极细胞感受野中心、强度跨度小于2个对数单位的测试刺激,会引发完整范围的分级反应。引发分级反应的测试刺激强度范围取决于背景条件。在存在周边背景的情况下,需要更高范围的对数测试强度来引发双极细胞的分级反应。但周边背景也可使双极细胞反应不饱和,从而在某些条件下提高敏感性。结果表明,敏感性控制的第二阶段由外网状层的水平细胞系统介导,并与光感受器中的适应效应相结合。

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