天花病毒的排泄。1. 患者咽喉、尿液及结膜中的病毒排泄。
Virus excretion in smallpox. 1. Excretion in the throat, urine, and conjunctiva of patients.
作者信息
Sarkar J K, Mitra A C, Mukherjee M K, De S K, Mazumdar D G
出版信息
Bull World Health Organ. 1973 May;48(5):517-22.
Abstract
Excretion of virus in the throat, urine, and conjunctiva of smallpox patients was studied daily for 2-3 weeks after the onset of fever. The virus titre in the throat and urine of haemorrhagic and confluent cases was higher than in discrete cases. The duration of virus excretion was also greater in confluent cases than in discrete cases. Conjunctival swabs from all 12 smallpox patients with conjunctivitis were positive for virus. The duration and titre of virus excretion in the throat, urine, and conjunctiva of patients were not related to their age or sex and did not depend on whether or not they had received a primary vaccination.
摘要
在天花患者发热开始后的2至3周内，每天对其咽喉、尿液和结膜中的病毒排泄情况进行研究。出血性和融合性病例的咽喉和尿液中的病毒滴度高于离散性病例。融合性病例的病毒排泄持续时间也比离散性病例更长。所有12例患有结膜炎的天花患者的结膜拭子病毒检测均呈阳性。患者咽喉、尿液和结膜中病毒排泄的持续时间和滴度与他们的年龄或性别无关，也不取决于他们是否接受过初次疫苗接种。
相似文献
1
Virus excretion in smallpox. 1. Excretion in the throat, urine, and conjunctiva of patients.天花病毒的排泄。1. 患者咽喉、尿液及结膜中的病毒排泄。
Bull World Health Organ. 1973 May;48(5):517-22.
2
Isolation of virus from the urine, conjunctiva and throat of smallpox cases.
Bull Calcutta Sch Trop Med. 1972 Jul;20(3):37-9.
3
Virus excretion in smallpox. 2. Excretion in the throats of household contacts.天花中的病毒排泄。2. 家庭接触者咽喉中的排泄情况。
Bull World Health Organ. 1973 May;48(5):523-7.
4
Variola virus in the throat of healthy contacts of small-pox cases.
Bull Calcutta Sch Trop Med. 1972 Oct;20(4):61-2.
5
Serial isolation of variola virus in the throat of household contacts of smallpox cases.
Bull Calcutta Sch Trop Med. 1973 Apr;21(2):21-2.
6
Duration of virus excretion in the throat of asymptomatic household contacts of smallpox patients.天花患者无症状家庭接触者咽喉部病毒排泄持续时间。
Indian J Med Res. 1974 Dec;62(12):1800-3.
7
Pattern of intrafamilial transmission of smallpox in Calcutta, India.印度加尔各答天花的家庭内传播模式。
Bull World Health Organ. 1974;51(3):219-25.
8
Virus content of smallpox scabs.天花痂皮的病毒含量
Bull World Health Organ. 1974;51(1):106-7.
9
Results of a virological study of smallpox convalescents and contacts: short communication.
J Hyg Epidemiol Microbiol Immunol. 1973 Mar;17(3):266-71.
10
Role of laboratory diagnosis in the smallpox eradication programme in India.实验室诊断在印度天花根除计划中的作用。
Indian J Public Health. 1978 Jan-Mar;22(1):113-9.
引用本文的文献
1
Decoding the mechanophysiology for inhaled onset of smallpox with model-based implications for mpox spread.解码天花吸入传播的机械生理学，并基于模型探讨猴痘传播的影响。
medRxiv. 2025 Jun 20:2025.06.17.25329814. doi: 10.1101/2025.06.17.25329814.
2
Ophthalmic manifestations of monkeypox infection.猴痘感染的眼部表现。
Indian J Ophthalmol. 2023 May;71(5):1687-1697. doi: 10.4103/ijo.IJO_2032_22.
3
Ophthalmic Features and Implications of Poxviruses: Lessons from Clinical and Basic Research.痘病毒的眼科特征及影响：来自临床和基础研究的经验教训
Microorganisms. 2022 Dec 15;10(12):2487. doi: 10.3390/microorganisms10122487.
4
A Review of Monkeypox Ocular Manifestations and Complications: Insights for the 2022 Outbreak.猴痘眼部表现及并发症综述：2022年疫情的见解
Ophthalmol Ther. 2023 Feb;12(1):55-69. doi: 10.1007/s40123-022-00626-4. Epub 2022 Dec 13.
5
Screening for Monkeypox Infection in Asymptomatic High-Risk-Behaviour Men Having Sex with Men (MSM).对有高危行为的男男性行为者（MSM）进行猴痘感染筛查。
Infect Dis Rep. 2022 Oct 17;14(5):794-797. doi: 10.3390/idr14050081.
6
Modelling of optimal vaccination strategies in response to a bioterrorism associated smallpox outbreak.应对与生物恐怖主义相关的天花爆发的最优疫苗接种策略建模。
Hum Vaccin Immunother. 2021 Mar 4;17(3):738-746. doi: 10.1080/21645515.2020.1800324. Epub 2020 Dec 2.
7
Intranasal monkeypox marmoset model: Prophylactic antibody treatment provides benefit against severe monkeypox virus disease.鼻内接种猴痘绒猴模型：预防性抗体治疗可有效预防严重猴痘病毒病。
PLoS Negl Trop Dis. 2018 Jun 21;12(6):e0006581. doi: 10.1371/journal.pntd.0006581. eCollection 2018 Jun.
8
Buccal viral DNA as a trigger for brincidofovir therapy in the mousepox model of smallpox.在小鼠痘病毒天花模型中，口腔病毒DNA作为布林西多福韦治疗的触发因素。
Antiviral Res. 2017 Mar;139:112-116. doi: 10.1016/j.antiviral.2016.12.015. Epub 2016 Dec 27.
9
Antibody therapeutics for Ebola virus disease.用于埃博拉病毒病的抗体疗法。
Curr Opin Virol. 2016 Apr;17:45-49. doi: 10.1016/j.coviro.2016.01.006. Epub 2016 Jan 27.
10
What was the primary mode of smallpox transmission? Implications for biodefense.天花的主要传播方式是什么？对生物防御的影响。
Front Cell Infect Microbiol. 2012 Nov 29;2:150. doi: 10.3389/fcimb.2012.00150. eCollection 2012.
本文引用的文献
1
Epidemiological studies in smallpox. A study of intrafamilial transmission in a series of 254 infected families.天花的流行病学研究。对254个受感染家庭的家庭内传播情况的研究。
Indian J Med Res. 1968 Dec;56(12):1826-54.
2
An airborne outbreak of smallpox in a German hospital and its significance with respect to other recent outbreaks in Europe.德国一家医院天花的空气传播疫情及其与欧洲近期其他疫情的关联
Bull World Health Organ. 1970;43(5):669-79.
3
Conjunctivitis and subclinical infection in smallpox.天花中的结膜炎与亚临床感染
J Hyg (Lond). 1969 Dec;67(4):631-6. doi: 10.1017/s002217240004208x.
4
Virulence of variola virus isolated from smallpox cases of varying severity.从不同严重程度天花病例中分离出的天花病毒的毒力。
Indian J Med Res. 1967 Jan;55(1):13-20.
5
Viraemia in haemorrhagic and other forms of smallpox.出血性天花及其他形式天花中的病毒血症
J Indian Med Assoc. 1966 Aug 1;47(3):112-4.
Zotero 插件