培养的人成纤维细胞中3-羟基-3-甲基戊二酰辅酶A还原酶活性的调节。正常受试者与纯合子家族性高胆固醇血症患者细胞的比较。 - Suppr

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超能文献

Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured human fibroblasts. Comparison of cells from a normal subject and from a patient with homozygous familial hypercholesterolemia.

作者信息

Brown M S, Dana S E, Goldstein J L

出版信息

J Biol Chem. 1974 Feb 10;249(3):789-96.

PMID:4359767

Abstract

摘要

相似文献

Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured human fibroblasts. Comparison of cells from a normal subject and from a patient with homozygous familial hypercholesterolemia.培养的人成纤维细胞中3-羟基-3-甲基戊二酰辅酶A还原酶活性的调节。正常受试者与纯合子家族性高胆固醇血症患者细胞的比较。

J Biol Chem. 1974 Feb 10;249(3):789-96.

Familial hypercholesterolemia: identification of a defect in the regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity associated with overproduction of cholesterol.家族性高胆固醇血症：与胆固醇过度产生相关的3-羟基-3-甲基戊二酰辅酶A还原酶活性调节缺陷的鉴定。

Proc Natl Acad Sci U S A. 1973 Oct;70(10):2804-8. doi: 10.1073/pnas.70.10.2804.

Familial hypercholesterolemia: defective binding of lipoproteins to cultured fibroblasts associated with impaired regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity.家族性高胆固醇血症：脂蛋白与培养的成纤维细胞结合缺陷，与3-羟基-3-甲基戊二酰辅酶A还原酶活性调节受损有关。

Proc Natl Acad Sci U S A. 1974 Mar;71(3):788-92. doi: 10.1073/pnas.71.3.788.

Suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and inhibition of growth of human fibroblasts by 7-ketocholesterol.7-酮胆固醇对3-羟基-3-甲基戊二酰辅酶A还原酶活性的抑制及对人成纤维细胞生长的抑制作用

J Biol Chem. 1974 Nov 25;249(22):7306-14.

Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts by lipoproteins.脂蛋白对人成纤维细胞中3-羟基-3-甲基戊二酰辅酶A还原酶活性的调节

Proc Natl Acad Sci U S A. 1973 Jul;70(7):2162-6. doi: 10.1073/pnas.70.7.2162.

Homozygous familial hypercholesterolemia: specificity of the biochemical defect in cultured cells and feasibility of prenatal detection.纯合子家族性高胆固醇血症：培养细胞中生化缺陷的特异性及产前检测的可行性

Am J Hum Genet. 1974 Mar;26(2):199-206.

3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human hair roots.人发根中的3-羟基-3-甲基戊二酰辅酶A还原酶活性

J Lipid Res. 1975 Jan;16(1):7-11.

Hyperlipidemia in coronary heart disease: a biochemical genetic approach.

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Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in hepatoma tissue culture cells by serum lipoproteins.血清脂蛋白对肝癌组织培养细胞中3-羟基-3-甲基戊二酰辅酶A还原酶的调节作用

J Biol Chem. 1974 Oct 10;249(19):6104-9.

Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and the esterification of cholesterol in human long term lymphoid cell lines.人长期淋巴细胞系中3-羟基-3-甲基戊二酰辅酶A还原酶活性及胆固醇酯化作用的调节

Biochemistry. 1976 Feb 10;15(3):521-8. doi: 10.1021/bi00648a011.

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