Afonso J F
West J Med. 1974 Jan;120(1):17-26.
Two of five women with mixed mesodermal tumor of the uterus are well more than ten years after therapy. A third was well when last seen two years after therapy and died at age 84 but autopsy was not done. Review of the literature and the reported experience indicates that this diagnosis should be suspected more often. Since histologic features may vary from one place to another within the lesion, accurate assessment requires examination of adequate specimens of the tumor. The mere presence of heterologous elements in an endometrial carcinoma changes the five-year survival rate from 85 percent to less than 35 percent. While total abdominal hysterectomy with bilateral salpingo-oophorectomy is mandatory, radiation therapy should be added more often than in the past, as it has been clearly shown that many of these tumors are radiosensitive.
患有子宫混合性中胚叶肿瘤的五名女性中有两名在接受治疗后健康存活超过十年。第三名女性在治疗后两年最后一次被见到时情况良好，84岁时去世，但未进行尸检。文献回顾和报告的经验表明，这种诊断应更频繁地被怀疑。由于病变内不同部位的组织学特征可能有所不同，准确评估需要检查足够的肿瘤标本。子宫内膜癌中单纯存在异源性成分会使五年生存率从85%降至不到35%。虽然全腹子宫切除加双侧输卵管卵巢切除是必要的，但放疗应比过去更频繁地添加，因为已经清楚表明这些肿瘤中的许多对放疗敏感。
