前列腺疾病患者血清中一种类似BB-肌酸激酶的荧光假象。
A fluorescent artefact resembling BB-creatine kinase in sera of patients with prostatic disease.
作者信息
Jaggarao N, Moss D W
出版信息
Clin Chim Acta. 1979 Mar 15;92(3):477-80. doi: 10.1016/0009-8981(79)90230-4.
A fluorescent zone with mobility towards the anode almost equal to that of human BB-creatine kinase has been detected after electrophoresis on cellulose acetate of sera from each of 28 patients with prostatic carcinoma. The zone is not due to the BB isoenzyme and its appearance does not depend on the presence of substrates of creatine kinase. It therefore appears to be a further example of a fluorescent artefact resembling a creatine kinase ieoenzyme. These observations indicate a need for caution in assessing the possible value of BB-creatine kinase in patients with prostatic disease.
在对28例前列腺癌患者的血清进行醋酸纤维素电泳后，检测到一个向阳极移动的荧光区，其迁移率几乎与人类BB型肌酸激酶相同。该区域并非由BB同工酶引起，其出现也不依赖于肌酸激酶底物的存在。因此，它似乎是类似于肌酸激酶同工酶的荧光假象的又一个例子。这些观察结果表明，在评估前列腺疾病患者中BB型肌酸激酶的潜在价值时需要谨慎。
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