3β-14-二羟基-21-氧代-23-去氧-5-β-强心甾-20(22)-烯内酯3-乙酸酯（AY-17,605）及结构相关化合物对牛心和大鼠脑核苷-3':5'-单磷酸磷酸二酯酶的抑制作用 - Suppr

Suppr

超能文献

Inhibition of beef heart and rat brain nucleoside-3':5'-monophosphate phosphodiesterase by 3beta-14-dihydroxy-21-oxo-23-desoxo-5-beta-card-20(22)-enolide 3-acetate (AY-17,605) and structurally related compounds.

作者信息

Lippmann W

出版信息

Experientia. 1974 Mar 15;30(3):237-9. doi: 10.1007/BF01934800.

DOI:10.1007/BF01934800

PMID:4363224

Abstract

摘要

相似文献

Inhibition of beef heart and rat brain nucleoside-3':5'-monophosphate phosphodiesterase by 3beta-14-dihydroxy-21-oxo-23-desoxo-5-beta-card-20(22)-enolide 3-acetate (AY-17,605) and structurally related compounds.3β-14-二羟基-21-氧代-23-去氧-5-β-强心甾-20(22)-烯内酯3-乙酸酯（AY-17,605）及结构相关化合物对牛心和大鼠脑核苷-3':5'-单磷酸磷酸二酯酶的抑制作用

Experientia. 1974 Mar 15;30(3):237-9. doi: 10.1007/BF01934800.

Studies on 3,7-dimethyl-1-(5-oxo-hexyl)-xanthine(BL 191). I. Cyclic 3',5'-nucleotide phosphodiesterase (PDE) and the inhibitory effect of BL 191 on PDE in rat brain and heart.3,7 - 二甲基 - 1 -（5 - 氧代己基）黄嘌呤（BL 191）的研究。I. 环3',5'-核苷酸磷酸二酯酶（PDE）以及BL 191对大鼠脑和心脏中PDE的抑制作用

Chem Pharm Bull (Tokyo). 1974 Mar;22(3):587-93. doi: 10.1248/cpb.22.587.

Inhibition of cyclic 3',5'-nucleotide phosphodiesterase activity by diuretics and other agents.利尿剂及其他药物对环3',5'-核苷酸磷酸二酯酶活性的抑制作用。

Experientia. 1973 Oct 15;29(10):1217-9. doi: 10.1007/BF01935080.

Effect of cyclic nucleotides on activity of cyclic 3',5'-adenosine monophosphate phosphodiesterase.环核苷酸对3',5'-环磷酸腺苷磷酸二酯酶活性的影响。

Biochem Pharmacol. 1973 Jan 15;22(2):221-8. doi: 10.1016/0006-2952(73)90275-x.

Na, K-activated ATPase activity during and after arrhythmic response to AY-22-241 in the canine heart.犬心脏对AY - 22 - 241心律失常反应期间及之后的钠钾激活ATP酶活性

Ann N Y Acad Sci. 1974;242(0):671-82. doi: 10.1111/j.1749-6632.1974.tb19125.x.

Competitive inhibition of beef heart cyclic AMP phosphodiesterase by cytokinins and related compounds.细胞分裂素及相关化合物对牛心环磷酸腺苷磷酸二酯酶的竞争性抑制作用。

Proc Natl Acad Sci U S A. 1974 Dec;71(12):4670-4. doi: 10.1073/pnas.71.12.4670.

1-Ethyl-4-(isopropylidenehydrazino)-1H-pyrazolo-(3,4-b)-pyridine-5-carboxylic acid, ethyl ester, hydrochloride (SQ 20009)--a potent new inhibitor of cyclic 3',5'-nucleotide phosphodiesterases.1-乙基-4-（亚异丙基肼基）-1H-吡唑并[3,4-b]吡啶-5-羧酸乙酯盐酸盐（SQ 20009）——一种新型强效环3',5'-核苷酸磷酸二酯酶抑制剂。

Biochem Pharmacol. 1972 Sep 15;21(18):2443-50. doi: 10.1016/0006-2952(72)90414-5.

Cyclic 3',5'-AMP phosphodiesterase in isolated fat cells. Simple and sensitive methods for the assay of phosphodiesterase activity in fat cells and studies of the enzyme inhibition by theophylline.分离脂肪细胞中的环3',5'-AMP磷酸二酯酶。脂肪细胞中磷酸二酯酶活性测定的简单灵敏方法及茶碱对该酶抑制作用的研究。

Pharmacology. 1972;7(2):65-77. doi: 10.1159/000136274.

Effect of glucagon, dibutyryl adenosine 3',5'-cyclic monophosphate and phosphodiesterase inhibitors on rat liver phosphorylase activity and adenosine 3',5'-cyclic monophosphate levels.胰高血糖素、二丁酰腺苷 3',5'-环磷酸单酯和磷酸二酯酶抑制剂对大鼠肝脏磷酸化酶活性及腺苷 3',5'-环磷酸单酯水平的影响。

Biochem Pharmacol. 1974 Aug;23(15):2139-46. doi: 10.1016/0006-2952(74)90579-6.

Immunological phagocytosis: effect of drugs on phosphodiesterase activity.免疫吞噬作用：药物对磷酸二酯酶活性的影响。

Experientia. 1974 Aug 15;30(8):945-6. doi: 10.1007/BF01938377.

引用本文的文献

Effects of [N-(2-oxo-3,5,7-cycloheptatrien-1-yl)] aminooxoacetic acid ethyl ester (AY-25,674) on cyclic 3',5'-nucleotide formation and phosphodiesterase activity.[N-(2-氧代-3,5,7-环庚三烯-1-基)]氨基氧代乙酸乙酯（AY-25,674）对环3',5'-核苷酸形成及磷酸二酯酶活性的影响。

Experientia. 1979 Jan 15;35(1):88-90. doi: 10.1007/BF01917895.

本文引用的文献

Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。

J Biol Chem. 1951 Nov;193(1):265-75.

The determination of enzyme inhibitor constants.酶抑制剂常数的测定

Biochem J. 1953 Aug;55(1):170-1. doi: 10.1042/bj0550170.

Analogues of 4-(3,4-dimethoxybenzyl)-2-imidazolidinone as potent inhibitors of rat erythrocyte adenosine cyclic 3',5'-phosphate phosphodiesterase.4-(3,4-二甲氧基苄基)-2-咪唑烷酮类似物作为大鼠红细胞腺苷环化3',5'-磷酸磷酸二酯酶的强效抑制剂

Mol Pharmacol. 1971 Jan;7(1):111-5.

Adenosine 3':5'-cyclic monophosphate phosphodieterase: kinetic and inhibitor studies.腺苷3':5'-环磷酸磷酸二酯酶：动力学与抑制剂研究

Biochem J. 1970 Dec;120(4):11P-12P. doi: 10.1042/bj1200011pb.

Preparation and properties of a cyclic 3',5'-nucleotide phosphodiesterase isolated from frog erythrocytes.从青蛙红细胞中分离出的一种环3',5'-核苷酸磷酸二酯酶的制备及性质

Arch Biochem Biophys. 1970 Apr;137(2):435-41. doi: 10.1016/0003-9861(70)90460-1.

The assay of adenosine 3',5'-cyclic monophosphate and guanosine 3',5'-cyclic monophosphate in biological materials by enzymatic radioisotopic displacement.通过酶促放射性同位素置换法对生物材料中3',5'-环磷酸腺苷和3',5'-环磷酸鸟苷进行测定。

Biochemistry. 1968 Dec;7(12):4177-81. doi: 10.1021/bi00852a006.

Cyclic AMP.环磷酸腺苷

Annu Rev Biochem. 1968;37:149-74. doi: 10.1146/annurev.bi.37.070168.001053.

Inhibition of cyclic 3',5'-nucleotide phosphodiesterase by phenothiazine and reserpine derivatives.吩噻嗪和利血平衍生物对环3',5'-核苷酸磷酸二酯酶的抑制作用。

Biochim Biophys Acta. 1968 Jun 18;161(1):267-9. doi: 10.1016/0005-2787(68)90321-3.

Properties of cyclic 3',5'-nucleotide phosphodiesterase from rat brain.大鼠脑环3',5'-核苷酸磷酸二酯酶的特性

Biochemistry. 1967 Apr;6(4):1079-87. doi: 10.1021/bi00856a017.

Purification and properties of 3',5'-cyclic nucleotide phosphodiesterase from dog heart.犬心脏3',5'-环核苷酸磷酸二酯酶的纯化及性质

Biochemistry. 1966 Jan;5(1):150-7. doi: 10.1021/bi00865a020.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验