3,7 - 二甲基 - 1 -（5 - 氧代己基）黄嘌呤（BL 191）的研究。I. 环3',5'-核苷酸磷酸二酯酶（PDE）以及BL 191对大鼠脑和心脏中PDE的抑制作用 - Suppr | 超能文献

Studies on 3,7-dimethyl-1-(5-oxo-hexyl)-xanthine(BL 191). I. Cyclic 3',5'-nucleotide phosphodiesterase (PDE) and the inhibitory effect of BL 191 on PDE in rat brain and heart.

作者信息

Hayashi S, Ozawa H

出版信息

Chem Pharm Bull (Tokyo). 1974 Mar;22(3):587-93. doi: 10.1248/cpb.22.587.

DOI:10.1248/cpb.22.587

Abstract

摘要

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。

相似文献

1

Studies on 3,7-dimethyl-1-(5-oxo-hexyl)-xanthine(BL 191). I. Cyclic 3',5'-nucleotide phosphodiesterase (PDE) and the inhibitory effect of BL 191 on PDE in rat brain and heart.3,7 - 二甲基 - 1 -（5 - 氧代己基）黄嘌呤（BL 191）的研究。I. 环3',5'-核苷酸磷酸二酯酶（PDE）以及BL 191对大鼠脑和心脏中PDE的抑制作用

Chem Pharm Bull (Tokyo). 1974 Mar;22(3):587-93. doi: 10.1248/cpb.22.587.

2

Studies on 3,7-dimethyl-1-(5-oxo-hexyl)-xanthine (BL 191): the inhibitory effect of BL 191 on PDE in various tissues of rats.

Jpn J Pharmacol. 1976 Feb(1):117-20. doi: 10.1254/jjp.26.117.

3

Studies on 3,7-dimethyl-1-(5-oxo-hexyl)-xanthine (BL 191). II. Effect of BL 191 on lipolysis in rat epididymal adipose tissue.3,7 - 二甲基 - 1 -（5 - 氧代己基）黄嘌呤（BL 191）的研究。II. BL 191对大鼠附睾脂肪组织脂解作用的影响。

Chem Pharm Bull (Tokyo). 1975 Dec;23(12):3119-24. doi: 10.1248/cpb.23.3119.

4

Effect of 3,7-dimethyl-1-(5-oxo-hexyl)xanthine and 1-hexyl-3,7-dimethyl xanthine on cyclic AMP phosphodiesterase of the human umbilical cord vessels.3,7 - 二甲基 - 1 -（5 - 氧代己基）黄嘌呤和1 - 己基 - 3,7 - 二甲基黄嘌呤对人脐带动脉环磷酸腺苷磷酸二酯酶的作用

Res Commun Chem Pathol Pharmacol. 1973 May;5(3):655-62.

5

[Xanthine oxidase--xanthines as a system of endogenous regulation of phosphodiesterase activity].[黄嘌呤氧化酶——作为磷酸二酯酶活性内源性调节系统的黄嘌呤]

Biull Eksp Biol Med. 1980 Dec;90(12):673-5.

6

Inhibition of beef heart and rat brain nucleoside-3':5'-monophosphate phosphodiesterase by 3beta-14-dihydroxy-21-oxo-23-desoxo-5-beta-card-20(22)-enolide 3-acetate (AY-17,605) and structurally related compounds.

Experientia. 1974 Mar 15;30(3):237-9. doi: 10.1007/BF01934800.

7

Phosphodiesterase inhibitory profile of some related xanthine derivatives pharmacologically active on the peripheral microcirculation.

Biochem Pharmacol. 1994 Mar 2;47(5):781-8. doi: 10.1016/0006-2952(94)90477-4.

8

Alkylxanthines: inhibition of adenosine-elicited accumulation of cyclic AMP in brain slices and of brain phosphodiesterase activity.烷基黄嘌呤：对脑片中腺苷诱导的环磷酸腺苷积累及脑磷酸二酯酶活性的抑制作用。

Life Sci. 1979 Jun 25;24(26):2475-82. doi: 10.1016/0024-3205(79)90458-2.

9

Studies on 3,7-dimethyl-1-(5-oxo-hexyl)-xanthine (BL 191). III. Effects of BL 191 and its metabolites on cyclic 3',5'-nucleotide phosphodiesterase and lipolytic activities.3,7-二甲基-1-(5-氧代己基)黄嘌呤（BL 191）的研究。III. BL 191及其代谢产物对环3',5'-核苷酸磷酸二酯酶和脂解活性的影响。

Chem Pharm Bull (Tokyo). 1976 Jun;24(6):1384-6. doi: 10.1248/cpb.24.1384.

10

Effect of cyclic nucleotides on activity of cyclic 3',5'-adenosine monophosphate phosphodiesterase.环核苷酸对3',5'-环磷酸腺苷磷酸二酯酶活性的影响。

Biochem Pharmacol. 1973 Jan 15;22(2):221-8. doi: 10.1016/0006-2952(73)90275-x.

引用本文的文献

1

The Impact of the Exposome on Alzheimer's Disease: The Influence of Nutrition.暴露组对阿尔茨海默病的影响：营养的作用

Int J Mol Sci. 2025 Mar 26;26(7):3015. doi: 10.3390/ijms26073015.

2

Bringing biocatalytic deuteration into the toolbox of asymmetric isotopic labelling techniques.将生物催化氘代引入不对称同位素标记技术工具箱。

Nat Commun. 2020 Mar 19;11(1):1454. doi: 10.1038/s41467-020-15310-z.

3

Pentoxifylline. A review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic efficacy.己酮可可碱。对其药效学和药代动力学特性以及治疗效果的综述。

Drugs. 1987 Jul;34(1):50-97. doi: 10.2165/00003495-198734010-00003.