蚕豆病患者血清谷草转氨酶、谷丙转氨酶、γ-谷氨酰转肽酶及谷氨酸脱氢酶水平

Serum glutamic oxalacetic transaminase, glutamic pyruvic transaminase, gamma-glutamyl transpeptidase and glutamic dehydrogenase levels in favism.

作者信息

Meloni T, Pilo G, Gallisai D, Dore A

出版信息

Acta Haematol. 1979;62(2):71-3. doi: 10.1159/000207541.

DOI:10.1159/000207541

Abstract

Serum GOT, GPT, gamma-GT and GLDH were determined in 15 G-6-PD-deficient subjects during a hemolytic crisis and hemoglobinuria due to ingestion of fresh fava beans. The same G-6-PD-deficient subjects were studied again 2 months after the crisis, when they were asymptomatic. 15 normal healthy children served as controls. A statistically significant increase, above normal, in serum GOT, GLDH and gamma-GT was observed in the favic subjects during the crisis. All the values reverted to normal in the asymptomatic period.

摘要

对15名葡萄糖-6-磷酸脱氢酶（G-6-PD）缺乏的受试者在因摄入新鲜蚕豆引发溶血性危机和血红蛋白尿期间测定了血清谷草转氨酶（GOT）、谷丙转氨酶（GPT）、γ-谷氨酰转肽酶（gamma-GT）和谷氨酸脱氢酶（GLDH）。在危机过后2个月，这些G-6-PD缺乏的受试者无症状时再次接受研究。15名正常健康儿童作为对照。在危机期间，蚕豆病受试者的血清GOT、GLDH和gamma-GT出现高于正常水平的统计学显著升高。在无症状期所有数值恢复正常。