儿童急性下呼吸道感染的病毒学检查结果及血气张力
Virological findings and blood gas tensions in acute lower respiratory tract infections in children.
作者信息
Simpson H, Matthew D J, Inglis J M, George E L
出版信息
Br Med J. 1974 Jun 22;2(5920):629-32. doi: 10.1136/bmj.2.5920.629.
Abstract
Sequential blood gas tensions and pH have been measured in 84 children selected from 486 admitted to hospital during a 15-month period with acute lower respiratory tract infections. Of those selected 73 were treated conservatively and 11 by intermittent positive-pressure ventilation; one infant in the latter group died. Respiratory syncytial virus (R.S.V.) was isolated from 24 out of 62 patients studied and the main pathogen in the most severely affected infants. Statistical analysis showed that age and R.S.V. infection were independent determinants of severity, as reflected by a peak Pco(2) measurement at the height of the illness (age, P < 0.01; R.S.V. 0.05 > P > 0.01).
摘要
在15个月期间因急性下呼吸道感染入院的486名儿童中选取了84名儿童，对其连续测量血气张力和pH值。在这些被选取的儿童中，73名接受了保守治疗，11名接受了间歇正压通气治疗；后一组中有一名婴儿死亡。在所研究的62名患者中，从24名患者体内分离出呼吸道合胞病毒（R.S.V.），且该病毒是病情最严重婴儿的主要病原体。统计分析表明，年龄和R.S.V.感染是病情严重程度的独立决定因素，这在疾病高峰期的最高Pco(2)测量值中得到体现（年龄，P < 0.01；R.S.V.，0.05 > P > 0.01）。
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