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成肌细胞中腺苷酸激酶和肌酸激酶活性的调节

Regulation of adenylate kinase and creatine kinase activities in myogenic cells.

作者信息

Tarikas H, Schubert D

出版信息

Proc Natl Acad Sci U S A. 1974 Jun;71(6):2377-81. doi: 10.1073/pnas.71.6.2377.

Abstract

The regulation of the specific activities of adenylate kinase (EC 2.7.4.3) and creatine kinase (EC 2.7.3.2) in myogenic cell lines is independent of cell fusion. The observed increases in enzyme specific activities are cell density dependent, and may be further broken down into contributions from an increase in enzyme activity per cell and a decrease in protein per cell. Only the former appears to be affected by medium conditioning.

摘要

在成肌细胞系中,腺苷酸激酶(EC 2.7.4.3)和肌酸激酶(EC 2.7.3.2)的比活性调节与细胞融合无关。观察到的酶比活性增加依赖于细胞密度,并且可以进一步细分为每个细胞酶活性增加和每个细胞蛋白质减少的贡献。似乎只有前者受培养基预处理的影响。

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