Lee H W, Lee P W, Tamura M, Tamura T, Okuno Y
Biken J. 1979 Jun;22(2):41-5.
The first case of epidemic hemorrhagic fever in Japan was seen in Osaka in 1960. The etiologic agent of this disease has not yet been isolated, but a close etiologic relation between Korean hemorrhagic fever and epidemic hemorrhagic fever in Japan has been suspected because of similarities in the clinical and pathological pictures of the two diseases. This relation has now been confirmed serologically by demonstrating specific immunofluorescent antibodies to Korean hemorrhagic fever virus in 19 of 20 sera obtained from subjects 7 to 17 years after an acute attack of epidemic hemorrhagic fever.
1960年，日本大阪出现了首例流行性出血热病例。该疾病的病原体尚未分离出来，但由于两种疾病在临床和病理表现上有相似之处，怀疑韩国出血热与日本流行性出血热之间存在密切的病因学关系。现在，通过在20份血清中的19份中检测到针对韩国出血热病毒的特异性免疫荧光抗体，从急性流行性出血热发作7至17年后的受试者中获得，血清学上证实了这种关系。
