与非哮喘患儿的兄弟姐妹相比，哮喘患儿病毒性呼吸道感染的频率更高。
Greater frequency of viral respiratory infections in asthmatic children as compared with their nonasthmatic siblings.
作者信息
Minor T E, Baker J W, Dick E C, DeMeo A N, Ouellette J J, Cohen M, Reed C E
出版信息
J Pediatr. 1974 Oct;85(4):472-7. doi: 10.1016/s0022-3476(74)80447-6.
Abstract
A longitudinal clincal and microbiologic surveillance was conducted from October to May, 1971-72, on 16 children with infectious asthma and 15 of their nonasthmatic siblings. Asthmatic children experienced a significantly greater frequency of viral respiratory infections than did nonasthmatic ones (5.1 vs. 3.8 per subject). This increased incidence appeared to be largely the result of a greater number of rhinovirus infections. While respiratory infections of identical etiology that occurred concurrently in an asthmatic and his sibling were equivalent in severity, illnesses were longer (but not significantly so) in asthmatic children.
摘要
1971年10月至1972年5月，对16名感染性哮喘儿童及其15名非哮喘兄弟姐妹进行了纵向临床和微生物学监测。哮喘儿童发生病毒性呼吸道感染的频率明显高于非哮喘儿童（每位受试者分别为5.1次和3.8次）。这种发病率的增加似乎主要是鼻病毒感染数量较多的结果。虽然哮喘儿童及其兄弟姐妹同时发生的病因相同的呼吸道感染严重程度相当，但哮喘儿童的病程较长（但差异不显著）。
相似文献
1
Greater frequency of viral respiratory infections in asthmatic children as compared with their nonasthmatic siblings.与非哮喘患儿的兄弟姐妹相比，哮喘患儿病毒性呼吸道感染的频率更高。
J Pediatr. 1974 Oct;85(4):472-7. doi: 10.1016/s0022-3476(74)80447-6.
2
Weekly monitoring of children with asthma for infections and illness during common cold seasons.在普通感冒季节，每周监测哮喘儿童的感染和疾病情况。
J Allergy Clin Immunol. 2010 May;125(5):1001-1006.e1. doi: 10.1016/j.jaci.2010.01.059. Epub 2010 Apr 14.
3
Prevalence of viral respiratory tract infections in children with asthma.哮喘患儿中病毒性呼吸道感染的患病率。
J Allergy Clin Immunol. 2007 Feb;119(2):314-21. doi: 10.1016/j.jaci.2006.08.041. Epub 2006 Nov 30.
4
[Virological research in acute respiratory diseases during 1969-70].[1969 - 1970年急性呼吸道疾病的病毒学研究]
Ann Sclavo. 1971 Sep-Oct;13(5):567-83.
5
Epidemiology of viral respiratory infections.病毒性呼吸道感染的流行病学
Am J Med. 2002 Apr 22;112 Suppl 6A:4S-12S. doi: 10.1016/s0002-9343(01)01058-0.
6
Etiology of upper-respiratory-tract illnesses among civilian adults.
JAMA. 1966 Jan 3;195(1):1-7.
7
The etiology of respiratory tract infections in a tropical country.
Am J Epidemiol. 1973 Jan;97(1):34-43. doi: 10.1093/oxfordjournals.aje.a121481.
8
[Virological surveillance of acute respiratory tract illnesses of children in Morioka, Japan. II. Rhinovirus infection].[日本盛冈市儿童急性呼吸道疾病的病毒学监测。II. 鼻病毒感染]
Kansenshogaku Zasshi. 1991 Oct;65(10):1286-96. doi: 10.11150/kansenshogakuzasshi1970.65.1286.
9
Respiratory viruses and atypical bacteria triggering severe asthma exacerbation in children.引发儿童严重哮喘发作的呼吸道病毒和非典型细菌。
Hong Kong Med J. 2013 Jun;19 Suppl 4:11-4.
10
The Seattle virus watch. V. Epidemiologic observations of rhinovirus infections, 1965-1969, in families with young children.西雅图病毒监测。五、1965 - 1969年在有幼儿家庭中鼻病毒感染的流行病学观察
Am J Epidemiol. 1975 Feb;101(2):122-43. doi: 10.1093/oxfordjournals.aje.a112078.
引用本文的文献
1
[Atopy and infections].[特应性与感染]
Rev Fr Allergol Immunol Clin. 2000 Jan;40(1):119-122. doi: 10.1016/S0335-7457(00)80034-9. Epub 2005 May 16.
2
[Viral infections and asthma].[病毒感染与哮喘]
Rev Fr Allergol Immunol Clin. 1996 Dec;36(8):950-954. doi: 10.1016/S0335-7457(96)80118-3. Epub 2005 May 16.
3
Parental Perception Towards Flu Vaccination for Asthmatic Children in Saudi Arabia.沙特阿拉伯父母对哮喘儿童流感疫苗接种的看法。
Cureus. 2019 Dec 25;11(12):e6460. doi: 10.7759/cureus.6460.
4
Increased rhinovirus replication in nasal mucosa cells in allergic subjects is associated with increased ICAM-1 levels and endosomal acidification and is inhibited by L-carbocisteine.变应性个体鼻黏膜细胞中鼻病毒的复制增加与 ICAM-1 水平升高和内体酸化有关，并可被 L-卡巴司汀抑制。
Immun Inflamm Dis. 2016 Apr 15;4(2):166-181. doi: 10.1002/iid3.102. eCollection 2016 Jun.
5
Virus infection-induced bronchial asthma exacerbation.病毒感染诱发的支气管哮喘加重
Pulm Med. 2012;2012:834826. doi: 10.1155/2012/834826. Epub 2012 Aug 23.
6
Influence of maternal asthma on the cause and severity of infant acute respiratory tract infections.母亲哮喘对婴儿急性呼吸道感染的病因和严重程度的影响。
J Allergy Clin Immunol. 2012 May;129(5):1236-42. doi: 10.1016/j.jaci.2012.01.045. Epub 2012 Feb 14.
7
Do rhinoviruses reduce the probability of viral co-detection during acute respiratory tract infections?鼻病毒会降低急性呼吸道感染期间病毒合并检测的概率吗？
J Clin Virol. 2009 May;45(1):10-5. doi: 10.1016/j.jcv.2009.03.008. Epub 2009 Apr 18.
8
The impact of respiratory viral infection on wheezing illnesses and asthma exacerbations.呼吸道病毒感染对喘息性疾病和哮喘发作的影响。
Immunol Allergy Clin North Am. 2008 Aug;28(3):539-61, viii. doi: 10.1016/j.iac.2008.03.001.
9
Human rhinoviruses: the cold wars resume.人鼻病毒：冷战再度上演。
J Clin Virol. 2008 Aug;42(4):297-320. doi: 10.1016/j.jcv.2008.04.002. Epub 2008 May 27.
10
Effects of viral upper respiratory illness on running gait.病毒性上呼吸道疾病对跑步步态的影响。
J Athl Train. 1997 Oct;32(4):309-14.
本文引用的文献
1
METHACHOLINE AEROSOL AS TEST FOR BRONCHIAL ASTHMA.乙酰甲胆碱气雾剂用于支气管哮喘的检测
Arch Intern Med. 1965 Apr;115:452-8. doi: 10.1001/archinte.1965.03860160078013.
2
ACUTE PHARYNGITIS AND TONSILLITIS IN UNIVERSITY OF WISCONSIN STUDENTS.威斯康星大学学生的急性咽炎和扁桃体炎
JAMA. 1964 Nov 23;190:699-708. doi: 10.1001/jama.1964.03070210005001.
3
Failure of inactivated influenza vaccine to protect an aged population.灭活流感疫苗未能保护老年人群。
JAMA. 1969 Oct 20;210(3):485-9.
4
Increased response of asthmatic subjects to methacholine after influenza vaccine.流感疫苗接种后哮喘患者对乙酰甲胆碱的反应增强。
J Allergy. 1965 Nov-Dec;36(6):558-63. doi: 10.1016/0021-8707(65)90193-0.
5
The bacterial flora of the upper respiratory tract in children with severe asthma.重度哮喘患儿上呼吸道的细菌菌群
J Allergy. 1968 Jun;41(6):319-25. doi: 10.1016/0021-8707(68)90074-9.
6
Correlation between increased bronchial response to acetylcholine and diminished metabolic and eosinopenic responses to epinephrine in asthma.哮喘患者中支气管对乙酰胆碱反应性增加与对肾上腺素代谢及嗜酸性粒细胞减少反应减弱之间的相关性。
J Allergy. 1970 Sep;46(3):178-89. doi: 10.1016/0021-8707(70)90096-1.
7
Reduced effect of epinephrine on circulating eosinophils in asthma and after beta-adrenergic blockade or Bordetella pertussis vaccine. With a note on eosinopenia after methacholine.
J Allergy. 1970 Aug;46(2):90-102. doi: 10.1016/0021-8707(70)90076-6.
8
Rhinovirus infections in hospitalized children. Provocative bacterial interrelationships.
Arch Environ Health. 1967 Mar;14(3):390-6. doi: 10.1080/00039896.1967.10664760.
9
Viruses as precipitants of asthmatic attacks in children.病毒作为儿童哮喘发作的诱发因素
JAMA. 1974 Jan 21;227(3):292-8.
10
The association of viral and bacterial respiratory infections with exacerbations of wheezing in young asthmatic children.病毒和细菌呼吸道感染与幼儿哮喘患儿喘息加重的关联。
J Pediatr. 1973 Apr;82(4):578-90. doi: 10.1016/s0022-3476(73)80582-7.
Zotero 插件