酵母中N-乙酰葡糖胺激酶的诱导
Induction of N-acetylglucosamine kinase in yeast.
作者信息
Bhattacharya A, Puri M, Datta A
出版信息
Biochem J. 1974 Aug;141(2):593-5. doi: 10.1042/bj1410593.
Abstract
The presence of N-acetylglucosamine is essential for the induced synthesis of N-acetylglucosamine kinase in Candida albicans. The enzyme synthesis stops and its concentration in the cells declines rapidly as soon as N-acetylglucosamine is removed from the medium. Experiments with RNA- and protein-synthesis inhibitors indicate that the appearance of new enzyme activity is dependent on concomitant new protein synthesis and the inducer operates at a transcriptional level.
摘要
N-乙酰葡糖胺的存在对于白色念珠菌中N-乙酰葡糖胺激酶的诱导合成至关重要。一旦从培养基中去除N-乙酰葡糖胺，酶的合成就会停止，其在细胞中的浓度也会迅速下降。用RNA和蛋白质合成抑制剂进行的实验表明，新酶活性的出现依赖于同时进行的新蛋白质合成，并且诱导剂在转录水平上起作用。
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本文引用的文献
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