N-乙酰甘露糖胺对白色念珠菌芽管形成及N-乙酰葡糖胺利用酶的无端诱导作用。
Gratuitous induction by N-acetylmannosamine of germ tube formation and enzymes for N-acetylglucosamine utilization in Candida albicans.
作者信息
Sullivan P A, Shepherd M G
出版信息
J Bacteriol. 1982 Sep;151(3):1118-22. doi: 10.1128/jb.151.3.1118-1122.1982.
Abstract
N-Acetylmannosamine did not support the growth of Candida albicans, and this sugar was not accumulated by cells. Incubation of starved yeast cells at 37 degrees C with N-acetylmannosamine plus glucose resulted in germ tube formation. Furthermore, N-acetylmannosamine alone induced the uptake system for N-acetylglucosamine and the enzymes of the N-acetylglucosamine catabolic pathway to the same extent as the natural substrate. Induction of the uptake system and the enzymes was observed at 28 degrees C without germ tube formation and at 37 degrees C with germ tube formation. N-Acetylmannosamine is thus a gratuitous inducer for enzymes of the N-acetylglucosamine pathway and germ tube formation in C. albicans.
摘要
N-乙酰甘露糖胺不支持白色念珠菌的生长，并且这种糖不会被细胞积累。将饥饿的酵母细胞在37℃下与N-乙酰甘露糖胺加葡萄糖一起孵育会导致芽管形成。此外，单独的N-乙酰甘露糖胺诱导N-乙酰葡糖胺摄取系统和N-乙酰葡糖胺分解代谢途径的酶，其程度与天然底物相同。在28℃无芽管形成时以及在37℃有芽管形成时均观察到摄取系统和酶的诱导。因此，N-乙酰甘露糖胺是白色念珠菌中N-乙酰葡糖胺途径的酶和芽管形成的 gratuitous诱导剂。 （注：gratuitous在这里可能是“安慰性的、 gratuitous诱导剂，具体意思需结合更多背景确定，此处按原文翻译）
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