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脑心肌炎病毒感染细胞提取物中病毒和细胞信使核糖核酸的翻译效率

Efficiency of translation of viral and cellular mRNA's in extracts from cells infected with encephalomyocarditis virus.

作者信息

Svitkin Y V, Ugarova T Y, Ginevskaya V A, Kalinina N O, Scarlat I V, Agol V I

出版信息

Intervirology. 1974;4(4):214-20. doi: 10.1159/000149965.

DOI:10.1159/000149965
PMID:4376807
Abstract

The relative efficiency of translation of host cell mRNA and encephalomyocarditis (emc) virus RNA has been investigated in cell-free preparations from uninfected and EMC virus-infected Drebs-II cells. The ability of cell-free extracts from infected cells to translate exogenously-added EMC virus RNA and total Krebs-II cell mRNA was markedly diminished, but no evidence for the selective inhibition of translation of host cell mRNA in these systems was obtained.

摘要

在未感染和感染脑心肌炎(EMC)病毒的Drebs-II细胞的无细胞制剂中,研究了宿主细胞mRNA和脑心肌炎病毒RNA的相对翻译效率。感染细胞的无细胞提取物翻译外源添加的EMC病毒RNA和总的Krebs-II细胞mRNA的能力显著降低,但在这些系统中未获得宿主细胞mRNA翻译被选择性抑制的证据。

相似文献

1
Efficiency of translation of viral and cellular mRNA's in extracts from cells infected with encephalomyocarditis virus.脑心肌炎病毒感染细胞提取物中病毒和细胞信使核糖核酸的翻译效率
Intervirology. 1974;4(4):214-20. doi: 10.1159/000149965.
2
Comparison of initiation rates of encephalomyocarditis virus and host protein synthesis in infected cells.感染细胞中脑心肌炎病毒与宿主蛋白质合成起始速率的比较。
J Virol. 1978 Sep;27(3):640-7. doi: 10.1128/JVI.27.3.640-647.1978.
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[Ability of translation factors from infected encephalomyocarditis viruses of ascites carcinoma cells to maintain the protein-synthetizing activity of cellular polyribosomes].[来自腹水癌细胞感染性脑心肌炎病毒的翻译因子维持细胞多核糖体蛋白质合成活性的能力]
Biokhimiia. 1984 Apr;49(4):629-32.
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Mechanism of interferon action: inhibition of viral messenger ribonucleic acid translation in L-cell extracts.干扰素作用机制:对L细胞提取物中病毒信使核糖核酸翻译的抑制作用
J Virol. 1972 Dec;10(6):1184-98. doi: 10.1128/JVI.10.6.1184-1198.1972.
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Cellular protein synthesis shutoff by mengovirus: translation of nonviral and viral mRNA's in extracts from uninfected and infected Ehrlich ascites tumor cells.脑心肌炎病毒导致的细胞蛋白质合成关闭:未感染和感染埃氏腹水瘤细胞提取物中病毒和非病毒信使核糖核酸的翻译
J Virol. 1976 Apr;18(1):182-94. doi: 10.1128/JVI.18.1.182-194.1976.
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[Effective cell-free system for translation of encephalomyocarditis virus RNA].[用于脑心肌炎病毒RNA翻译的高效无细胞系统]
Dokl Akad Nauk SSSR. 1978;238(3):744-7.
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In vitro translation of encephalomyocarditis viral RNA: synthesis of capsid precursor-like polypeptides.脑心肌炎病毒RNA的体外翻译:衣壳前体样多肽的合成。
Virology. 1976 Apr;70(2):484-92. doi: 10.1016/0042-6822(76)90289-0.
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[Translation of cellular and viral information RNA in extracts from cells infected with encephalomyocarditis viruses].
Dokl Akad Nauk SSSR. 1974 Feb 11;214(5):1210-3.
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Encephalomyocarditis virus RNA. II. Polyadenylic acid requirement for efficient translation.脑心肌炎病毒RNA。II. 有效翻译对聚腺苷酸的需求。
J Virol. 1977 Aug;23(2):338-44. doi: 10.1128/JVI.23.2.338-344.1977.
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Translational control of protein synthesis after infection by vesicular stomatitis virus.水泡性口炎病毒感染后蛋白质合成的翻译调控
J Virol. 1980 Dec;36(3):719-33. doi: 10.1128/JVI.36.3.719-733.1980.

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J Virol. 1996 Dec;70(12):8993-6. doi: 10.1128/JVI.70.12.8993-8996.1996.
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Activation of the translational suppressor 4E-BP1 following infection with encephalomyocarditis virus and poliovirus.脑心肌炎病毒和脊髓灰质炎病毒感染后翻译抑制因子4E-BP1的激活。
Proc Natl Acad Sci U S A. 1996 May 28;93(11):5578-83. doi: 10.1073/pnas.93.11.5578.
3
Translational elongation rate changes in encephalomyocarditis virus-infected and interferon-treated cells.
脑心肌炎病毒感染及干扰素处理细胞中翻译延伸速率的变化
J Virol. 1981 Aug;39(2):573-83. doi: 10.1128/JVI.39.2.573-583.1981.