脑心肌炎病毒感染细胞提取物中病毒和细胞信使核糖核酸的翻译效率
Efficiency of translation of viral and cellular mRNA's in extracts from cells infected with encephalomyocarditis virus.
作者信息
Svitkin Y V, Ugarova T Y, Ginevskaya V A, Kalinina N O, Scarlat I V, Agol V I
出版信息
Intervirology. 1974;4(4):214-20. doi: 10.1159/000149965.
PMID:4376807
Abstract
The relative efficiency of translation of host cell mRNA and encephalomyocarditis (emc) virus RNA has been investigated in cell-free preparations from uninfected and EMC virus-infected Drebs-II cells. The ability of cell-free extracts from infected cells to translate exogenously-added EMC virus RNA and total Krebs-II cell mRNA was markedly diminished, but no evidence for the selective inhibition of translation of host cell mRNA in these systems was obtained.
摘要
在未感染和感染脑心肌炎（EMC）病毒的Drebs-II细胞的无细胞制剂中，研究了宿主细胞mRNA和脑心肌炎病毒RNA的相对翻译效率。感染细胞的无细胞提取物翻译外源添加的EMC病毒RNA和总的Krebs-II细胞mRNA的能力显著降低，但在这些系统中未获得宿主细胞mRNA翻译被选择性抑制的证据。
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