• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Induction of cystathionase in human foetal liver.人胎儿肝脏中胱硫醚酶的诱导
Biochem J. 1974 Dec;144(3):607-9. doi: 10.1042/bj1440607.
2
Induction of cystathionase in foetal rat liver explants. Effects of dexamethasone, N-6, O-2 -dibutyryladenosine 3,5 -monophosphate and glucagon in vitro.
Biochim Biophys Acta. 1975 Jul 14;399(1):113-23. doi: 10.1016/0304-4165(75)90217-2.
3
Influence of glucagon, 6-N,2'-O-dibutyryladenosine 3':5'-cyclic monophosphate and triamcinolone on the arginine synthetase system in perinatal rat liver.胰高血糖素、6 - N，2'- O - 二丁酰腺苷3':5'-环磷酸单酯和曲安西龙对围产期大鼠肝脏精氨酸合成酶系统的影响。
Biochem J. 1972 Jan;126(1):89-98. doi: 10.1042/bj1260089.
4
Enzymic differentiation in cultured foetal hepatocytes of the rat. Induction of serine dehydratase activity by dexamethasone and dibutyryl cyclic AMP.大鼠培养胎肝细胞中的酶分化。地塞米松和二丁酰环磷腺苷对丝氨酸脱水酶活性的诱导作用。
Differentiation. 1983;24(3):234-8. doi: 10.1111/j.1432-0436.1983.tb01325.x.
5
Induction of tyrosine aminotransferase synthesis in isolated liver cell suspensions. Absolute dependence of induction on glucocorticoids and glucagon or cyclic AMP.在分离的肝细胞悬液中酪氨酸转氨酶合成的诱导。诱导对糖皮质激素和胰高血糖素或环磷酸腺苷的绝对依赖性。
J Biol Chem. 1977 Oct 10;252(19):6783-91.
6
Regulation of coenzyme A biosynthesis by glucagon and glucocorticoid in adult rat liver parenchymal cells.胰高血糖素和糖皮质激素对成年大鼠肝实质细胞辅酶A生物合成的调节
Biochem J. 1980 Apr 15;188(1):175-84. doi: 10.1042/bj1880175.
7
Multihormonal control of tyrosine aminotransferase in isolated liver cells.分离肝细胞中酪氨酸转氨酶的多激素调控
Monogr Endocrinol. 1979;12:219-41. doi: 10.1007/978-3-642-81265-1_12.
8
Changes in the activities of the enzymes of urea synthesis caused by dexamethasone and dibutyryladenosine 3':5'-cyclic monophosphate in foetal rat liver maintained in organ culture.地塞米松和二丁酰腺苷3':5'-环磷酸在器官培养中对胎鼠肝脏尿素合成酶活性的影响。
Biochem J. 1976 Nov 15;160(2):159-62. doi: 10.1042/bj1600159.
9
Induction of the five urea-cycle enzymes by glucagon in cultured foetal rat hepatocytes.胰高血糖素对培养的胎鼠肝细胞中五种尿素循环酶的诱导作用。
Differentiation. 1987;35(3):212-8. doi: 10.1111/j.1432-0436.1987.tb00171.x.
10
Stimulation of ornithine decarboxylase and nuclear RNA polymerase activity in rat liver by glucagon and dibutyryl cyclic amp.胰高血糖素和二丁酰环磷腺苷对大鼠肝脏鸟氨酸脱羧酶及核RNA聚合酶活性的刺激作用。
Acta Endocrinol (Copenh). 1973 Aug;73(4):794-800. doi: 10.1530/acta.0.0730794.

引用本文的文献

1
Total sulfur amino acid requirements are higher during late gestation compared with early gestation in healthy Canadian pregnancies in a repeated-measures trial.在一项重复测量试验中，与妊娠早期相比，健康加拿大妊娠的晚期总硫氨基酸需求更高。
Am J Clin Nutr. 2024 Oct;120(4):973-983. doi: 10.1016/j.ajcnut.2024.07.034. Epub 2024 Aug 10.
2
Effect of High-Dose Cysteine Supplementation on Erythrocyte Glutathione: A Double-Blinded, Randomized Placebo-Controlled Pilot Study in Critically Ill Neonates.大剂量补充半胱氨酸对新生儿红细胞谷胱甘肽的影响：一项针对危重新生儿的双盲、随机、安慰剂对照试验研究
JPEN J Parenter Enteral Nutr. 2016 Feb;40(2):226-34. doi: 10.1177/0148607114546375. Epub 2014 Aug 19.
3
Cord blood glutathione depletion in preterm infants: correlation with maternal cysteine depletion.早产儿脐血谷胱甘肽耗竭：与母体半胱氨酸耗竭的相关性。
PLoS One. 2011;6(11):e27626. doi: 10.1371/journal.pone.0027626. Epub 2011 Nov 16.
4
H2S signals through protein S-sulfhydration.H2S 通过蛋白质 S-巯基化传递信号。
Sci Signal. 2009 Nov 10;2(96):ra72. doi: 10.1126/scisignal.2000464.
5
Metabolism of methionine in the newborn infant: response to the parenteral and enteral administration of nutrients.新生儿甲硫氨酸的代谢：对肠外和肠内营养物质给药的反应。
Pediatr Res. 2008 Oct;64(4):381-6. doi: 10.1203/PDR.0b013e318180e499.
6
Cysteine, cystine or N-acetylcysteine supplementation in parenterally fed neonates.肠胃外营养的新生儿补充半胱氨酸、胱氨酸或N-乙酰半胱氨酸。
Cochrane Database Syst Rev. 2006 Oct 18;2006(4):CD004869. doi: 10.1002/14651858.CD004869.pub2.
7
Murine cystathionine gamma-lyase: complete cDNA and genomic sequences, promoter activity, tissue distribution and developmental expression.小鼠胱硫醚γ-裂解酶：完整的cDNA和基因组序列、启动子活性、组织分布及发育表达
Biochem J. 2004 Jul 1;381(Pt 1):113-23. doi: 10.1042/BJ20040243.

本文引用的文献

1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
The amino acid requirements of man. XIII. The sparing effect of cystine on the methionine requirement.人类的氨基酸需求。十三。胱氨酸对蛋氨酸需求的节约作用。
J Biol Chem. 1955 Oct;216(2):753-73.
3
A spectrophotometric method for the direct determination of cysteine in the presence of other naturally occurring amino acids.一种在其他天然存在的氨基酸存在下直接测定半胱氨酸的分光光度法。
Biochem J. 1967 Aug;104(2):627-33. doi: 10.1042/bj1040627.
4
Absence of cystathionase in human fetal liver: is cystine essential?人胎儿肝脏中缺乏胱硫醚酶：胱氨酸是必需的吗？
Science. 1970 Jul 3;169(3940):74-6. doi: 10.1126/science.169.3940.74.
5
Cystathionase: immunochemical evidence for absence from human fetal liver.胱硫醚酶：人胎儿肝脏中不存在的免疫化学证据。
Pediatr Res. 1972 Oct;6(10):773-8. doi: 10.1203/00006450-197210000-00005.
6
Development of mammalian sulfur metabolism: absence of cystathionase in human fetal tissues.哺乳动物硫代谢的发育：人胎儿组织中胱硫醚酶的缺失。
Pediatr Res. 1972 Jun;6(6):538-47. doi: 10.1203/00006450-197206000-00002.
7
Influence of glucagon, 6-N,2'-O-dibutyryladenosine 3':5'-cyclic monophosphate and triamcinolone on the arginine synthetase system in perinatal rat liver.胰高血糖素、6 - N，2'- O - 二丁酰腺苷3':5'-环磷酸单酯和曲安西龙对围产期大鼠肝脏精氨酸合成酶系统的影响。
Biochem J. 1972 Jan;126(1):89-98. doi: 10.1042/bj1260089.

人胎儿肝脏中胱硫醚酶的诱导

Induction of cystathionase in human foetal liver.

作者信息

Heinonen K, Räihä N C

出版信息

Biochem J. 1974 Dec;144(3):607-9. doi: 10.1042/bj1440607.

DOI:10.1042/bj1440607
PMID:4377660
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1168542/
Abstract

Incubation of liver explants from second-trimester human foetuses with dexamethasone, glucagon or dibutyryl cyclic AMP (plus theophylline) increased the activity of liver cystathionase from unmeasurable or trace values to adult values. Simultaneous incubation with cycloheximide or actinomycin D inhibited this effect.

摘要

将孕中期人类胎儿的肝脏外植体与地塞米松、胰高血糖素或二丁酰环磷腺苷（加茶碱）一起孵育，可使肝脏胱硫醚酶的活性从不可测或微量值增加到成人水平。同时用环己酰亚胺或放线菌素D孵育可抑制这种作用。