Kay K
Environ Health Perspect. 1974 Dec;9:193-5. doi: 10.1289/ehp.749193.
Substantial quantities of mineral silicates are used as carriers for agricultural pest control agents. Most of this material is applied by air dissemination, either dry or as a droplet spray. Therefore, pulmonary and gastric deposition of the mineral carriers (and active agents) will occur among pesticide application personnel and some proportion of the general population in the vicinity of pest control operations-to the extent that particle size of the disseminated material is below the critical 5mum respirable diameter. Furthermore, ingestion of particulates deposited on food crops may be expected as well as mineral finding its way into drinking water supplies. It has been found that the silicates widely used in America can contain three forms of asbestos, anthophyllite, tremolite, and chrysolite. Of these, anthophyllite and chrysotile have been found associated with a neoplastic outcome after many years of exposure. It is therefore proposed that comprehensive mineralogical investigation of pesticide carriers is warranted, including epidemiological and clinical study of formulation and application personnel as well as exposed nonoccupational populations.
大量的矿物硅酸盐被用作农业害虫防治剂的载体。这种材料大多通过空气传播来施用,或是干式的,或是以液滴喷雾的形式。因此,在农药施用人员以及害虫防治作业附近的部分普通人群中,矿物载体(以及活性剂)会在肺部和胃部沉积——前提是传播材料的粒径低于关键的5微米可吸入直径。此外,预计会有沉积在粮食作物上的颗粒物被摄入,同时矿物也会进入饮用水供应中。已经发现,美国广泛使用的硅酸盐可能含有三种石棉形式,直闪石、透辉石和温石棉。其中,直闪石和温石棉在多年接触后已被发现与肿瘤发生有关。因此,建议对农药载体进行全面的矿物学调查,包括对制剂和施用人员以及暴露的非职业人群进行流行病学和临床研究。