Osmon D C, Golden C J, Purisch A D, Hammeke T A, Blume H G
Int J Neurosci. 1979;9(1):1-9.
The present study was designed to examine the capability of a standardized battery of Luria's qualitative neuropsychological techniques in discriminating between right, left and diffuse brain-injured subjects. A total of sixty medically confirmed brain-damaged subjects were equally divided among the three groups. Subjects were assigned to two groups (right, left) according to medically proven lateralized brain injury to either the right or left hemisphere in the absence of verifiable insult to the opposite hemisphere. A third group was also selected in which medical evidence confirmed damage to both hemispheres (diffuse group). All three groups were matched for age and education. All subjects were tested on a standardized version of 269 Luria's qualitative neuropsychological test items. The items were divided into 11 sections based upon Luria's theory of brain function. Each of the 11 sections plus a right and a left hemisphere scale as well as an overall impairment scale yielded 14 summary measures of performance representing several areas of neuropsychological ability and overall severity of brain dysfunction. Analysis of variance and discriminant analysis were used to compare the three groups on these 14 summary measures. Analysis of variance revealed on significant difference between the three groups on the Left scale with the left group performing poorest. Discriminant analysis predicted the status of 59 of 60 subjects correctly (98% hit rate). The implication of the lack of significant simple relationships (ANOVA) and the complex interrelationships found using the discriminant analysis were discussed in terms of the support these results provide for Luria's theory of brain function. The specific qualitative aspects of the test battery and their use in the diagnosis of lateralized brain injury were also discussed. Indications for future research were pointed out.
本研究旨在检验一套标准化的鲁利亚定性神经心理学技术在区分右侧、左侧和弥漫性脑损伤受试者方面的能力。共有60名经医学确诊的脑损伤受试者被平均分为三组。根据医学证实的单侧脑损伤（右侧或左侧半球）且对侧半球无可证实的损伤，将受试者分为两组（右侧、左侧）。还选择了第三组，其中医学证据证实双侧半球均有损伤（弥漫性组）。所有三组在年龄和教育程度上进行了匹配。所有受试者都接受了269项鲁利亚定性神经心理学测试项目的标准化版本测试。这些项目根据鲁利亚的脑功能理论分为11个部分。11个部分中的每一个加上右侧和左侧半球量表以及整体损伤量表，产生了14个表现的汇总测量指标，代表了神经心理学能力的几个领域和脑功能障碍的整体严重程度。使用方差分析和判别分析在这14个汇总测量指标上比较三组。方差分析显示三组在左侧量表上存在显著差异，左侧组表现最差。判别分析正确预测了60名受试者中的59名的状态（命中率98%）。根据这些结果为鲁利亚脑功能理论提供的支持，讨论了缺乏显著简单关系（方差分析）和使用判别分析发现的复杂相互关系的含义。还讨论了测试组的具体定性方面及其在单侧脑损伤诊断中的应用。指出了未来研究的方向。
