Fogstrup J, With T K
J Clin Pathol. 1979 Feb;32(2):109-12. doi: 10.1136/jcp.32.2.109.
Determination of total porphyrin with a rapid and east method (ion exchange; spectrophotometry) was performed on 57 morning urine samples from laboratory personnel, 59 arbitrary day urine samples from blood donors, and 90 24-hour urines from medical inpatients. The upper reference limit for morning urine was 0.32 mumol/l but even a value as high as 0.7 mumol/l was found. In the donor urines the upper limit was 0.155 mumol/l. The 24-hour urines showed an upper reference limit of 271 microgram/24 h. These values are in good agreement with values from the literature, mostly based on extraction analyses. Tracings of the absorption curves in the region of 380--430 nm were performed in all analyses and showed that the non-porphyrin absorption was close to linear in most cases. Studies of porphyric urines gave no support to the claim that preformed porphyrins not formed from porphobilinogen are excreted in this disease.
采用一种快速简便的方法（离子交换；分光光度法）对57份实验室人员的晨尿样本、59份献血者任意时段的尿液样本以及90份住院患者的24小时尿液样本进行了总卟啉测定。晨尿的参考上限为0.32μmol/L，但甚至发现有高达0.7μmol/L的值。献血者尿液的上限为0.155μmol/L。24小时尿液的参考上限为271μg/24小时。这些值与文献中的值非常一致，文献中的值大多基于萃取分析。在所有分析中均对380 - 430nm区域的吸收曲线进行了描记，结果表明在大多数情况下非卟啉吸收接近线性。对卟啉尿的研究不支持下述观点，即在这种疾病中会排出并非由胆色素原形成的预先形成的卟啉。
