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镰状细胞病的血清蛋白谱

Serum protein profile in sickle cell disease.

作者信息

Isichei U P

出版信息

J Clin Pathol. 1979 Feb;32(2):117-21. doi: 10.1136/jcp.32.2.117.

Abstract

The total protein, albumin, globulin, and immunoglobulin levels of sera from 96 children with homozygous sickle cell disease were studied. A comparison of the results with the levels found in a control group of normal children of the same age shows that the sicklers have higher total protein, globulin, and IgM levels. The amounts of albumin and IgA seen were almost the same in both groups. The IgG levels differed considerably, the sicklers having only about half the quantity seen in normal children.

摘要

对96名纯合子镰状细胞病患儿血清中的总蛋白、白蛋白、球蛋白和免疫球蛋白水平进行了研究。将结果与同年龄正常儿童对照组的水平进行比较,发现镰状细胞病患儿的总蛋白、球蛋白和IgM水平较高。两组中白蛋白和IgA的含量几乎相同。IgG水平差异很大,镰状细胞病患儿的IgG量仅约为正常儿童的一半。

本文引用的文献

2
The development of the serum protein pattern in Africans.非洲人血清蛋白模式的发展。
J Clin Pathol. 1961 Nov;14(6):644-53. doi: 10.1136/jcp.14.6.644.
5
The serum proteins of healthy adult Nigerians.健康成年尼日利亚人的血清蛋白
J Clin Pathol. 1957 Aug;10(3):276-9. doi: 10.1136/jcp.10.3.276.
7
Pneumococcal meningitis in sickle-cell anemia.镰状细胞贫血中的肺炎球菌性脑膜炎
N Engl J Med. 1966 May 5;274(18):1006-8. doi: 10.1056/NEJM196605052741806.

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