Isichei U P
J Clin Pathol. 1979 Feb;32(2):117-21. doi: 10.1136/jcp.32.2.117.
The total protein, albumin, globulin, and immunoglobulin levels of sera from 96 children with homozygous sickle cell disease were studied. A comparison of the results with the levels found in a control group of normal children of the same age shows that the sicklers have higher total protein, globulin, and IgM levels. The amounts of albumin and IgA seen were almost the same in both groups. The IgG levels differed considerably, the sicklers having only about half the quantity seen in normal children.
对96名纯合子镰状细胞病患儿血清中的总蛋白、白蛋白、球蛋白和免疫球蛋白水平进行了研究。将结果与同年龄正常儿童对照组的水平进行比较,发现镰状细胞病患儿的总蛋白、球蛋白和IgM水平较高。两组中白蛋白和IgA的含量几乎相同。IgG水平差异很大,镰状细胞病患儿的IgG量仅约为正常儿童的一半。