Piris J, Whitehead R
J Clin Pathol. 1979 Feb;32(2):171-8. doi: 10.1136/jcp.32.2.171.
The number of gastrin-producing cells in biopsy specimens from the gastric and duodenal mucosae in 19 duodenal ulcer patients was quantitated using a morphometric method. The level of immunoreactive gastrin in a sample of fasting serum obtained at the time of the biopsy was measured by radioimmunoassay. The results show no significant difference when compared with those from a group of normal control volunteers. Moreover, there was no correlation between the numbers of gastrin-producing cells and the fasting serum gastrin level in either controls or duodenal ulcer patients.
采用形态计量学方法对19例十二指肠溃疡患者胃和十二指肠黏膜活检标本中胃泌素产生细胞的数量进行了定量分析。通过放射免疫分析法测定活检时采集的空腹血清样本中免疫反应性胃泌素的水平。与一组正常对照志愿者的结果相比，结果显示无显著差异。此外，无论是对照组还是十二指肠溃疡患者，胃泌素产生细胞的数量与空腹血清胃泌素水平之间均无相关性。
