十二指肠溃疡患者的胃泌素细胞和空腹胃泌素水平：一项基于多个活检标本的定量研究。
Gastin cells and fasting gastrin levels in duodenal ulcer patients: a quantitative study based on multiple biopsy specimens.
作者信息
Piris J, Whitehead R
出版信息
J Clin Pathol. 1979 Feb;32(2):171-8. doi: 10.1136/jcp.32.2.171.
Abstract
The number of gastrin-producing cells in biopsy specimens from the gastric and duodenal mucosae in 19 duodenal ulcer patients was quantitated using a morphometric method. The level of immunoreactive gastrin in a sample of fasting serum obtained at the time of the biopsy was measured by radioimmunoassay. The results show no significant difference when compared with those from a group of normal control volunteers. Moreover, there was no correlation between the numbers of gastrin-producing cells and the fasting serum gastrin level in either controls or duodenal ulcer patients.
摘要
采用形态计量学方法对19例十二指肠溃疡患者胃和十二指肠黏膜活检标本中胃泌素产生细胞的数量进行了定量分析。通过放射免疫分析法测定活检时采集的空腹血清样本中免疫反应性胃泌素的水平。与一组正常对照志愿者的结果相比，结果显示无显著差异。此外，无论是对照组还是十二指肠溃疡患者，胃泌素产生细胞的数量与空腹血清胃泌素水平之间均无相关性。
相似文献
1
Gastin cells and fasting gastrin levels in duodenal ulcer patients: a quantitative study based on multiple biopsy specimens.十二指肠溃疡患者的胃泌素细胞和空腹胃泌素水平：一项基于多个活检标本的定量研究。
J Clin Pathol. 1979 Feb;32(2):171-8. doi: 10.1136/jcp.32.2.171.
2
Gastrin and somatostatin cells in dyspeptic patients with and without duodenal ulcer: a quantitative study based on multiple biopsy specimens.有和无十二指肠溃疡的消化不良患者中的胃泌素和生长抑素细胞：一项基于多个活检标本的定量研究
J Gastroenterol Hepatol. 1989 Jan-Feb;4(1):41-7. doi: 10.1111/j.1440-1746.1989.tb00805.x.
3
4
[Gastrin cell (G cell) population of the gastroduodenal mucosa in patients with gastric ulcer and duodenal ulcer (author's transl)].胃溃疡和十二指肠溃疡患者胃十二指肠黏膜中的胃泌素细胞（G细胞）群体（作者译）
Nihon Shokakibyo Gakkai Zasshi. 1978 Sep;75(9):1312-21.
5
[Helicobacter pylori, endocrine cells of the gastric mucosa, and their function in duodenal ulcer].[幽门螺杆菌、胃黏膜内分泌细胞及其在十二指肠溃疡中的作用]
Arkh Patol. 1996 Jan-Feb;58(1):33-7.
6
G-cell populations in resected stomachs from gastric and duodenal ulcer patients.胃溃疡和十二指肠溃疡患者切除胃中的G细胞群体。
Gastroenterology. 1980 Mar;78(3):498-504.
7
8
Gastric enterochromaffin-like (ECL) cells in hypergastrinaemic duodenal ulcer disease.高胃泌素血症性十二指肠溃疡病中的胃肠嗜铬样（ECL）细胞
Gut. 1990 Feb;31(2):144-7. doi: 10.1136/gut.31.2.144.
9
Helicobacter pylori and duodenal ulcer: evidence for a histamine pathways-involving link.幽门螺杆菌与十二指肠溃疡：涉及组胺途径关联的证据。
Am J Gastroenterol. 1996 Nov;91(11):2338-43.
10
[Gastroduodenal incretory cells in duodenal ulcer with different levels of gastric secretion].
Arkh Patol. 1990;52(10):20-5.
引用本文的文献
1
G- and D-cell populations, serum and tissue concentrations of gastrin and somatostatin in patients with peptic ulcer diseases.消化性溃疡疾病患者的G细胞和D细胞群体、胃泌素和生长抑素的血清及组织浓度。
Korean J Intern Med. 1993 Jan;8(1):1-7. doi: 10.3904/kjim.1993.8.1.1.
2
Quantification of human gastric G cell density in endoscopic biopsy specimens: effect of shape of specimen.内镜活检标本中人类胃G细胞密度的定量分析：标本形状的影响
J Clin Pathol. 1980 Jun;33(6):513-6. doi: 10.1136/jcp.33.6.513.
3
A method for the quantification of human gastric G cell density in endoscopic biopsy specimens.一种在内镜活检标本中定量检测人胃G细胞密度的方法。
J Clin Pathol. 1981 May;34(5):514-8. doi: 10.1136/jcp.34.5.514.
4
A study on the distribution of G-cells in human gastric mucosa.一项关于人胃黏膜中G细胞分布的研究。
Gastroenterol Jpn. 1984 Feb;19(1):41-52. doi: 10.1007/BF02774645.
5
Antral gastrin-producing G-cells and somatostatin-producing D-cells in different states of gastric acid secretion.处于不同胃酸分泌状态下的胃窦部产胃泌素G细胞和产生长抑素D细胞。
Gut. 1982 Apr;23(4):285-91. doi: 10.1136/gut.23.4.285.
6
Relationship between gastrin cell number, serum, antral mucosa and luminal gastrin concentration and gastric acidity in antral atrophic gastritis.胃窦萎缩性胃炎中胃泌素细胞数量、血清、胃窦黏膜及管腔胃泌素浓度与胃酸度之间的关系。
Gut. 1990 Mar;31(3):279-81. doi: 10.1136/gut.31.3.279.
本文引用的文献
1
Enzyme-labeled antibodies: preparation and application for the localization of antigens.酶标抗体：抗原定位的制备与应用
J Histochem Cytochem. 1966 Dec;14(12):929-31. doi: 10.1177/14.12.929.
2
Principles and methods for the morphometric study of the lung and other organs.肺及其他器官形态测量研究的原理与方法。
Lab Invest. 1963 Feb;12:131-55.
3
Relations between serum gastrin levels and rates of gastric hydrochloric acid secretion.血清胃泌素水平与胃盐酸分泌率之间的关系。
N Engl J Med. 1971 Feb 25;284(8):408-12. doi: 10.1056/NEJM197102252840803.
4
Serum gastrin levels in patients with peptic ulcer disease.消化性溃疡病患者的血清胃泌素水平。
Gastroenterology. 1970 Jul;59(1):6-12.
5
Serum gastrin in duodenal ulcer. I. Basal levels and effect of food and atropine.十二指肠溃疡患者的血清胃泌素。I. 基础水平以及食物和阿托品的影响。
Gut. 1971 Nov;12(11):899-902. doi: 10.1136/gut.12.11.899.
6
A method for the quantitation of small intestinal biopsy specimens.一种小肠活检标本的定量方法。
J Clin Pathol. 1972 Mar;25(3):243-6. doi: 10.1136/jcp.25.3.243.
7
Radio-immunoassay of gastrin in human plasma.人血浆中胃泌素的放射免疫测定
J Physiol. 1972 Jan;220(2):499-510.
8
Determination of gastrin in serum. An evaluation of the reliability of a radioimmunoassay.血清胃泌素的测定。放射免疫分析法可靠性的评估。
Scand J Gastroenterol. 1973;8(2):101-12.
9
Differences in rates of gastrin release in normal persons and patients with duodenal-ulcer disease.
N Engl J Med. 1973 Jan 11;288(2):64-6. doi: 10.1056/NEJM197301112880202.
10
Zollinger-Ellison syndrome type 1: clinical and pathological correlations in a case.1型佐林格-埃利森综合征：1例临床与病理相关性分析
Gut. 1973 Jan;14(1):25-9. doi: 10.1136/gut.14.1.25.
Zotero 插件