限制氨基酸供应对离体灌注豚鼠乳腺的影响。

Effects of restriction of amino acid supply to the isolated perfused guinea-pig mammary gland.

作者信息

Mepham T B, Peters A R, Alexandrov S

出版信息

J Dairy Res. 1979 Jan;46(1):69-73. doi: 10.1017/s0022029900016861.

DOI:10.1017/s0022029900016861

Abstract

When individual essential amino acids were omitted for periods of 40--100 min from the infusate substrate solution in isolated perfused guinea-pig mammary gland experiments, uptake of methionine, tyrosine, phenylalanine, histidine and tryptophan (group 1) was significantly depressed by a mean of 49.8%, whereas the remaining essential amino acids (group 2) showed no significant decrease in uptake. During depletion periods oxidation of [14C]amino acids was increased. The possible significance of the differences in absorption between the 2 groups of amino acids is discussed.

摘要

在离体灌注豚鼠乳腺实验中，当从输注底物溶液中去除单个必需氨基酸40 - 100分钟时，蛋氨酸、酪氨酸、苯丙氨酸、组氨酸和色氨酸（第1组）的摄取量平均显著降低了49.8%，而其余必需氨基酸（第2组）的摄取量没有显著下降。在去除氨基酸期间，[14C]氨基酸的氧化增加。讨论了两组氨基酸吸收差异的可能意义。