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Metabolism and mechanism of action of oestrogens. XII. Structure and mechanism of formation of water-soluble and protein-bound metabolites of oestrone in rat-liver microsomes in vitro and in vivo.

作者信息

Marks F, Hecker E

出版信息

Biochim Biophys Acta. 1969;187(2):250-65. doi: 10.1016/0005-2760(69)90035-6.

DOI:10.1016/0005-2760(69)90035-6
PMID:4390401
Abstract
摘要

相似文献

1
Metabolism and mechanism of action of oestrogens. XII. Structure and mechanism of formation of water-soluble and protein-bound metabolites of oestrone in rat-liver microsomes in vitro and in vivo.雌激素的代谢与作用机制。十二、雌酮在大鼠肝脏微粒体中体外及体内水溶性和蛋白结合代谢物的结构与形成机制
Biochim Biophys Acta. 1969;187(2):250-65. doi: 10.1016/0005-2760(69)90035-6.
2
[On the metabolism and mechanism of action of estrogens. 8. The biogenesis and metabolism of 2-hydroxyestrone in relation to the formation of protein-bound and water soluble estrone metabolites and to NADPH oxidation in rat liver microsomes].
Hoppe Seylers Z Physiol Chem. 1966;345(1):22-40.
3
[On the formation of water-soluble metabolites from estrone in rat liver microsomes].[关于大鼠肝微粒体中雌酮形成水溶性代谢物的研究]
Biochim Biophys Acta. 1965 Dec 16;111(2):546-8.
4
[Metabolism and mechanism of action of estrogens. X. Relations between estrogen metabolism and lipid peroxidation in rat liver microsomes].[雌激素的代谢与作用机制。X. 大鼠肝微粒体中雌激素代谢与脂质过氧化之间的关系]
Hoppe Seylers Z Physiol Chem. 1968 May;349(5):523-32.
5
Effect of 17 alpha-ethinylestradiol on the biliary metabolites of 17 beta-[6,7-3H2]estradiol in the rat.17α-乙炔雌二醇对大鼠体内17β-[6,7-³H₂]雌二醇胆汁代谢产物的影响。
Biochim Biophys Acta. 1971 Mar 16;231(2):399-405.
6
Nature of the water-soluble estrogen metabolites formed by rat liver in vitro.大鼠肝脏体外形成的水溶性雌激素代谢物的性质。
Can J Biochem. 1965 Oct;43(10):1774-6. doi: 10.1139/o65-196.
7
Nature of the water-soluble metabolites of 7,12-dimethylbenza(a)-anthracene formed by liver microsomes of normal and 3-methylcholanthrene-treated rats.正常大鼠和经3-甲基胆蒽处理的大鼠肝脏微粒体形成的7,12-二甲基苯并(a)蒽水溶性代谢物的性质
Cancer Res. 1970 Jun;30(6):1715-21.
8
[Comparative changes in the metabolism of estrone sulfate and estrone in rat liver cell fractions].[大鼠肝细胞组分中硫酸雌酮和雌酮代谢的比较变化]
Biochim Biophys Acta. 1967 Feb 14;137(1):196-8.
9
Synthesis and antiestrogenic activity of 2,4-bis(bromomethyl)-estrone methyl ether: a bifunctional alkylating steroid.2,4-双（溴甲基）-雌酮甲醚的合成及其抗雌激素活性：一种双功能烷基化甾体
Steroids. 1974 Jul;24(1):63-77. doi: 10.1016/0039-128x(74)90046-4.
10
Studies on the mechanism of estrogen biosynthesis. 3. The stereochemistry of aromatization of C19 and C18 steroids.雌激素生物合成机制的研究。3. C19和C18甾体的芳构化立体化学。
Biochemistry. 1968 Jan;7(1):33-40. doi: 10.1021/bi00841a005.

引用本文的文献

1
Interaction of estrone and estradiol with DNA and protein of liver and kidney in rat and hamster in vivo and in vitro.雌酮和雌二醇在大鼠和仓鼠体内及体外与肝脏和肾脏的DNA和蛋白质的相互作用。
Arch Toxicol. 1984 Jul;55(2):97-103. doi: 10.1007/BF00346046.
2
Modulation of estrogen-induced carcinogenesis by chemical modifications.通过化学修饰对雌激素诱导的致癌作用进行调节。
Arch Toxicol. 1984 Jul;55(2):119-22. doi: 10.1007/BF00346049.
3
Metabolism of stilbene estrogens and steroidal estrogens in relation to carcinogenicity.芪类雌激素和甾体雌激素的代谢与致癌性的关系。
Arch Toxicol. 1984 Jul;55(2):104-9. doi: 10.1007/BF00346047.
4
[On the biochemical mechanism of tumorgenesis in the mouse skin. I. Distribution and metabolism of intragastrically administered 9,10-dimethyl-(1,2)-benzanthracene in the mouse].[关于小鼠皮肤肿瘤发生的生化机制。I. 经胃给予小鼠的9,10-二甲基-（1,2）-苯并蒽的分布与代谢]
Z Krebsforsch. 1968;71(2):153-66.
5
Semiquinone anion radicals of catechol(amine)s, catechol estrogens, and their metal ion complexes.儿茶酚（胺）、儿茶酚雌激素及其金属离子络合物的半醌阴离子自由基。
Environ Health Perspect. 1985 Dec;64:185-98. doi: 10.1289/ehp.8564185.
6
Target organ-specific inactivation of drug metabolizing enzymes in kidney of hamsters treated with estradiol.用雌二醇处理的仓鼠肾脏中药物代谢酶的靶器官特异性失活。
Mol Cell Biochem. 1992 Mar 4;110(1):31-9. doi: 10.1007/BF02385003.
7
Effect of rifampicin treatment on the metabolism of oestradiol and 17alpha-ethinyloestradiol by human liver microsomes.利福平治疗对人肝微粒体中雌二醇和17α-乙炔雌二醇代谢的影响。
Eur J Clin Pharmacol. 1975 Jun 13;8(5):301-7. doi: 10.1007/BF00562654.
8
Decreased liver cytochrome P-450 in rats caused by norethindrone or ethynyloestradiol.炔诺酮或炔雌醇导致大鼠肝脏细胞色素P - 450减少。
Biochem J. 1977 Jul 15;166(1):57-64. doi: 10.1042/bj1660057.
9
The significance of covalent binding of catechols to proteins in vivo.儿茶酚在体内与蛋白质共价结合的意义。
Arch Toxicol. 1977 Dec 30;39(1-2):31-9. doi: 10.1007/BF00343273.
10
Structural modifications in contraceptive steroids altering their metabolism and toxicity.改变代谢和毒性的避孕甾体的结构修饰。
Arch Toxicol. 1977 Dec 30;39(1-2):13-9. doi: 10.1007/BF00343271.