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Nature of the water-soluble metabolites of 7,12-dimethylbenza(a)-anthracene formed by liver microsomes of normal and 3-methylcholanthrene-treated rats.

作者信息

Jellinck P H, Smith G, Fletcher R

出版信息

Cancer Res. 1970 Jun;30(6):1715-21.

PMID:4394040
Abstract
摘要

相似文献

1
Nature of the water-soluble metabolites of 7,12-dimethylbenza(a)-anthracene formed by liver microsomes of normal and 3-methylcholanthrene-treated rats.正常大鼠和经3-甲基胆蒽处理的大鼠肝脏微粒体形成的7,12-二甲基苯并(a)蒽水溶性代谢物的性质
Cancer Res. 1970 Jun;30(6):1715-21.
2
Regioselectivity and stereoselectivity in the metabolism of trans-1,2-dihydroxy-1,2-dihydrobenz[a]anthracene by rat liver microsomes.大鼠肝微粒体对反式-1,2-二羟基-1,2-二氢苯并[a]蒽代谢的区域选择性和立体选择性
Mol Pharmacol. 1983 Jul;24(1):115-23.
3
Glutathione conjugates as metabolites of benz[a]anthracene.
Xenobiotica. 1975 Jul;5(7):439-48. doi: 10.3109/00498257509056114.
4
N-ethylmaleimide adduct of 7,12-dimethylbenzanthracene. Properties and metabolism by rat liver microsomes.7,12-二甲基苯并蒽的N-乙基马来酰亚胺加合物。大鼠肝微粒体的性质与代谢
Biochem Pharmacol. 1972 Jun 1;21(11):1603-8. doi: 10.1016/0006-2952(72)90310-3.
5
The highly tumorigenic 3,4-dihydrodiol is a principal metabolite formed from dibenzo[a,h]anthracene by liver enzymes.
Mol Pharmacol. 1979 Sep;16(2):643-55.
6
The formation of "K-region" epoxides as hepatic microsomal metabolites of 7-methylbenz(a)anthracene and 7,12-dimethylbenz(a)anthracene and their 7-hydroxymethyl derivatives.
Biochem Pharmacol. 1973 Nov 15;22(22):2853-67. doi: 10.1016/0006-2952(73)90152-4.
7
Metabolism of 7,12-dimethylbenz(a)anthracene and 7-hydroxymethyl-12-methylbenz(a)anthracene by rat liver and microsomes.大鼠肝脏及微粒体对7,12-二甲基苯并(a)蒽和7-羟甲基-12-甲基苯并(a)蒽的代谢
Cancer Res. 1981 Apr;41(4):1559-64.
8
Metabolism of benz(a)anthracene epoxides by rat-liver.
Biochem Pharmacol. 1974 Sep 15;23(18):2547-55. doi: 10.1016/0006-2952(74)90177-4.
9
3-Hydroxymethylcholanthrene: metabolic formation from 3-methylcholanthrene and stereoselective metabolism by rat liver microsomes.
Drug Metab Dispos. 1996 May;24(5):595-601.
10
Microsomal metabolism of dibenz[a,c]anthracene, dibenz[a,h]anthracene and dibenz[a,j]anthracene to bis-dihydrodiols and polyhydroxylated products.
Chem Biol Interact. 1991;80(3):261-79. doi: 10.1016/0009-2797(91)90087-n.

引用本文的文献

1
Metabolism of (4- 14 C)oestradiol by oestrogen-induced uterine peroxidase.雌激素诱导的子宫过氧化物酶对（4-¹⁴C）雌二醇的代谢作用
Biochem J. 1972 Apr;127(3):481-7. doi: 10.1042/bj1270481.
2
The persistence of unmetabolized 3H-7,12-dimethylbenz(a)anthracene in regenerating rat liver.未代谢的3H-7,12-二甲基苯并(a)蒽在再生大鼠肝脏中的持久性。
Br J Cancer. 1975 Oct;32(4):440-50. doi: 10.1038/bjc.1975.245.
3
Metabolism of 7,12,-dimethylbenz(a)anthracene by normal and regenerating rat livers.正常和再生大鼠肝脏对7,12 - 二甲基苯并(a)蒽的代谢
Br J Cancer. 1977 Jun;35(6):713-21. doi: 10.1038/bjc.1977.112.
4
Polychlorinated biphenyl(s) as a promotor in experimental hepatocarcinogenesis in rats.多氯联苯作为大鼠实验性肝癌发生的促进剂
Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1976 Dec 9;87(3):257-66. doi: 10.1007/BF00506498.