Drach G W, Perin R, Jacobs S
J Urol. 1979 May;121(5):564-7. doi: 10.1016/s0022-5347(17)56881-0.
Eighty patients with proved calcium urolithiasis participated in an outpatient study designed to define the most likely metabolic problem related to the cause of the stone disease. Diagnostic categories included absorptive hypercalciuria (33 patients), renal leak hypercalciuria (20 patients), hypomagnesiumuria (27 patients), hyperuricemia and hyperuricuria (16 patients), hyperoxaluria (15 patients), normal stone-former (4 patients), renal tubular acidosis (2 patients) and suspicion of hyperparathyroidism (7 patients). Of the 80 patients 40 had more than 1 defect. Patients with a high suspicion of hyperparathyroidism were excluded from the study. Based on these criteria treatment plans incorporating medications, diet or both were instituted. Of 21 patients observed for greater than 2 years 90 per cent have shown no new stone disease.
80例经证实患有钙尿路结石的患者参与了一项门诊研究，该研究旨在确定与结石病病因最相关的代谢问题。诊断类别包括吸收性高钙尿症（33例患者）、肾性漏出性高钙尿症（20例患者）、低镁尿症（27例患者）、高尿酸血症和高尿酸尿症（16例患者）、高草酸尿症（15例患者）、正常结石形成者（4例患者）、肾小管酸中毒（2例患者）以及疑似甲状旁腺功能亢进（7例患者）。80例患者中，40例存在不止一种缺陷。高度怀疑甲状旁腺功能亢进的患者被排除在研究之外。基于这些标准，制定了包含药物治疗、饮食或两者结合的治疗方案。在观察超过2年的21例患者中，90%未出现新的结石病。
