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Investigation of the component reactions of oxidative sterol demethylation. Oxidation of a 4 alpha-methyl sterol to a 4 alpha-carboxylic acid during cholesterol biosynthesis.

作者信息

Miller W L, Gaylor J L

出版信息

J Biol Chem. 1970 Oct 25;245(20):5369-74.

PMID:4394228
Abstract
摘要

相似文献

1
Investigation of the component reactions of oxidative sterol demethylation. Oxidation of a 4 alpha-methyl sterol to a 4 alpha-carboxylic acid during cholesterol biosynthesis.氧化甾醇去甲基化的组成反应研究。胆固醇生物合成过程中4α-甲基甾醇氧化为4α-羧酸。
J Biol Chem. 1970 Oct 25;245(20):5369-74.
2
Investigation of the component reactions of oxidative sterol demethylation. Oxidation of a 4,4-dimethyl sterol to a 4 beta-methyl-4 alpha-carboxylic acid during cholesterol biosynthesis.氧化甾醇去甲基化的组成反应研究。在胆固醇生物合成过程中，一种4,4-二甲基甾醇氧化为4β-甲基-4α-羧酸。
J Biol Chem. 1970 Oct 25;245(20):5375-81.
3
A carboxylic acid intermediate of lanostenol demethylation.羊毛甾醇去甲基化的羧酸中间体。
Biochem Biophys Res Commun. 1970 Sep 30;40(6):1452-4. doi: 10.1016/0006-291x(70)90030-6.
4
Investigation of the component reactions of oxidative sterol demethylation. Formation and metabolism of 3-ketosteroid intermediates.氧化甾醇脱甲基化的组成反应研究。3-酮甾体中间体的形成与代谢。
J Biol Chem. 1968 Nov 10;243(21):5546-55.
5
Investigation of the component reactions of oxidative demethylation of sterols. Metabolism of 4 -hydroxymethyl steroids.
J Biol Chem. 1971 Aug 25;246(16):5147-53.
6
Enzymic formation of esters of methyl sterol precursors of cholesterol.
J Lipid Res. 1971 May;12(3):270-6.
7
Investigation of the component reactions of oxidative sterol demethylation. Role of an endogenous microsomal source of reducing equivalents.氧化甾醇脱甲基作用的组分反应研究。内源性微粒体还原当量来源的作用。
J Biol Chem. 1972 Dec 10;247(23):7650-6.
8
Investigation of the component reactions of oxidative sterol demethylation. Study of the aerobic and anaerobic processes.
Biochemistry. 1967 Sep;6(9):2673-8. doi: 10.1021/bi00861a005.
9
Cytochrome P-450-dependent oxidation of lanosterol in cholesterol biosynthesis. Microsomal electron transport and C-32 demethylation.胆固醇生物合成中细胞色素P-450依赖的羊毛甾醇氧化。微粒体电子传递与C-32去甲基化。
J Biol Chem. 1984 Nov 10;259(21):13402-12.
10
Partial purification of a microsomal sterol 4 -carboxylic acid decarboxylase.微粒体甾醇4-羧酸脱羧酶的部分纯化
J Biol Chem. 1972 Jan 10;247(1):9-15.

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1
Human hepatic metabolism of the anti-osteoporosis drug eldecalcitol involves sterol C4-methyl oxidase.人肝脏代谢抗骨质疏松药物艾地骨化醇涉及固醇 C4-甲基氧化酶。
Pharmacol Res Perspect. 2015 Mar;3(2):e00120. doi: 10.1002/prp2.120. Epub 2015 Feb 10.
2
Lipid biomarkers of oxidative stress in a genetic mouse model of Smith-Lemli-Opitz syndrome.氧化应激的脂质生物标志物在 Smith-Lemli-Opitz 综合征的遗传小鼠模型中。
J Inherit Metab Dis. 2013 Jan;36(1):113-22. doi: 10.1007/s10545-012-9504-z. Epub 2012 Jun 21.
3
Gene expression profiles in testis of pigs with extreme high and low levels of androstenone.
具有极高和极低雄烯酮水平的猪睾丸中的基因表达谱。
BMC Genomics. 2007 Nov 7;8:405. doi: 10.1186/1471-2164-8-405.
4
Characterization of the Saccharomyces cerevisiae ERG26 gene encoding the C-3 sterol dehydrogenase (C-4 decarboxylase) involved in sterol biosynthesis.酿酒酵母ERG26基因的特性分析，该基因编码参与甾醇生物合成的C-3甾醇脱氢酶（C-4脱羧酶）。
Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13794-9. doi: 10.1073/pnas.95.23.13794.
5
Microsomal enzymes of cholesterol biosynthesis from lanosterol: a progress report.从羊毛甾醇合成胆固醇的微粒体酶：进展报告。
Lipids. 1982 Mar;17(3):250-6. doi: 10.1007/BF02535112.
6
Regulation of the sequencing in sterol biosynthesis.固醇生物合成中测序的调控。
Lipids. 1971 Apr;6(4):219-24. doi: 10.1007/BF02538391.
7
Studies on the mechanism and regulation of C-4 demethylation in cholesterol biosynthesis. The role of adenosine 3':5'-cyclic monophosphate.胆固醇生物合成中C-4去甲基化的机制与调控研究。3':5'-环磷酸腺苷的作用。
Biochem J. 1971 Nov;125(2):625-34. doi: 10.1042/bj1250625.
8
Studies on the control of cholesterol biosynthesis: the adenosine 3':5'-cyclic monophosphate-dependent accumulation of a steroid carboxylic acid.胆固醇生物合成调控的研究：一种甾体羧酸的3':5'-环磷酸腺苷依赖性积累。
Biochem J. 1971 Jun;123(2):275-8. doi: 10.1042/bj1230275.
9
The pathway for the conversion of dihydroagnosterol into cholesterol in rat liver.大鼠肝脏中双氢阿格诺甾醇转化为胆固醇的途径。
Biochem J. 1977 Jul 15;166(1):11-5. doi: 10.1042/bj1660011.
10
Lipids of yeasts.酵母的脂质
Bacteriol Rev. 1975 Sep;39(3):197-231. doi: 10.1128/br.39.3.197-231.1975.