Leishman A W, Thirkettle J L, Allen B R, Dixon R A
Br Med J. 1970 Nov 7;4(5731):342-4. doi: 10.1136/bmj.4.5731.342.
In controlled trials of the beta-adrenergic blocking drugs oxprenolol and practolol in hypertension both drugs were well tolerated without side effects and caused statistically significant non-postural reduction of blood pressure. In less than half the patients on eitherdrug the reduction of blood pressure was clinically adequate. No attempt was made to compare the two drugs.
在β-肾上腺素能阻滞剂氧烯洛尔和心得宁治疗高血压的对照试验中,两种药物耐受性良好,无副作用,且能使血压产生具有统计学意义的非体位性下降。使用这两种药物的患者中,不到一半的患者血压下降幅度达到临床治疗要求。未对这两种药物进行比较。