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遗传转化过程中的DNA摄取与细胞包膜的生长区域。

DNA uptake during genetic transformation and the growing zone of the cell envelope.

作者信息

Tomasz A, Zanati E, Ziegler R

出版信息

Proc Natl Acad Sci U S A. 1971 Aug;68(8):1848-52. doi: 10.1073/pnas.68.8.1848.

DOI:10.1073/pnas.68.8.1848
PMID:4399665
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC389306/
Abstract

Continuous cellular incorporation of choline molecules is essential for DNA binding to competent pneumococci. The choline molecules are incorporated into the cell surface at the equatorial region of the cocci. As a working hypothesis, it is proposed that DNA molecules enter these bacteria at the growing zone(s) of the cell envelope.

摘要

胆碱分子的持续细胞内掺入对于DNA与感受态肺炎球菌的结合至关重要。胆碱分子在球菌的赤道区域掺入细胞表面。作为一个工作假设，有人提出DNA分子在细胞膜的生长区域进入这些细菌。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e334/389306/e513cfba4740/pnas00083-0191-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e334/389306/a7d5c51605ab/pnas00083-0191-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e334/389306/e513cfba4740/pnas00083-0191-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e334/389306/a7d5c51605ab/pnas00083-0191-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e334/389306/e513cfba4740/pnas00083-0191-b.jpg

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DNA uptake during genetic transformation and the growing zone of the cell envelope.遗传转化过程中的DNA摄取与细胞包膜的生长区域。
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本文引用的文献

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Nutritional Requirements of the Pneumococcus: I. Growth Factors for Types I, II, V, VII, VIII.肺炎球菌的营养需求：I. I型、II型、V型、VII型、VIII型的生长因子
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Competence for deoxyribonucleic acid uptake and deoxyribonuclease action external to cells in the genetic transformation of Diplococcus pneumoniae.肺炎双球菌基因转化过程中细胞外脱氧核糖核酸摄取能力及脱氧核糖核酸酶作用
J Bacteriol. 1973 Apr;114(1):152-63. doi: 10.1128/jb.114.1.152-163.1973.
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遗传转化。一、肺炎球菌转化过程中DNA的细胞内掺入
Biochim Biophys Acta. 1957 Oct;26(1):68-82. doi: 10.1016/0006-3002(57)90055-0.
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Autolytic enzyme system of Streptococcus faecalis. 3. Localization of the autolysin at the sites of cell wall synthesis.粪链球菌的自溶酶系统。3. 自溶素在细胞壁合成位点的定位。
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Autolytic activity associated with competent group H streptococci.与具感受态的H组链球菌相关的自溶活性。
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Radioautographic evidence for equatorial wall growth in a gram-positive bacterium. Segregation of choline-3H-labeled teichoic acid.革兰氏阳性细菌赤道壁生长的放射自显影证据。胆碱-3H标记的磷壁酸的分离。
J Cell Biol. 1970 Dec;47(3):786-90. doi: 10.1083/jcb.47.3.786.
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Binding of the competence factor to receptors in the spheroplast membrane of pneumococci.感受态因子与肺炎球菌原生质球膜中受体的结合。
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Multiple antibiotic resistance in a bacterium with suppressed autolytic system.具有受抑制自溶系统的细菌中的多重抗生素耐药性
Nature. 1970 Jul 11;227(5254):138-40. doi: 10.1038/227138a0.
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Choline-containing teichoic acid as a structural component of pneumococcal cell wall and its role in sensitivity to lysis by an autolytic enzyme.含胆碱磷壁酸作为肺炎球菌细胞壁的结构成分及其在对自溶酶裂解敏感性中的作用。
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