Suppr超能文献

通过塑料径迹探测器扫描得到的LAMPF生物医学通道下高传能线密度π介子剂量轮廓。

High-LET pion dose contours under the LAMPF biomedical channel by plastic track detector scanning.

作者信息

Knowles H B, Ruddy F H, West G W, Kligerman M M

出版信息

Med Phys. 1979 Jan-Feb;6(1):32-8. doi: 10.1118/1.594635.

Abstract

Cellulose-nitrate plastic track detectors have been tested as high spatial-resolution dosimeters at the Biomedical Channel of the Clinton P. Anderson Meson Physics Facility (LAMPF) at the Los Alamos Scientific Laboratory during pilot clinical trials with negative pi mesons (pions). Six plots of dose contours are presented. Reliable macrodosimetry with track detectors would in principle require detector calibration for the particular conditions of geometry and beam parameters in every case but it is interesting that absolute dose values, estimated from data taken with a quite different calibration geometry, were within 20% of agreement with dose values obtained by electronic dosimetry methods. The track detectors measure only the high linear energy transfer (LET) components produced by the pion beam; it is these components which are of special interest in the negative-pion therapy program. Plastic track detectors appear to have many favorable properties for pion dosimetry.

摘要

在洛斯阿拉莫斯科学实验室的克林顿·P·安德森介子物理设施(LAMPF)生物医学通道进行的负π介子(π介子)试点临床试验中,纤维素硝酸盐塑料径迹探测器已作为高空间分辨率剂量计进行了测试。给出了六幅剂量轮廓图。原则上,使用径迹探测器进行可靠的宏观剂量测定需要针对每种情况下的特定几何条件和束流参数对探测器进行校准,但有趣的是,根据采用完全不同校准几何结构获取的数据估算的绝对剂量值,与通过电子剂量测定方法获得的剂量值的一致性在20%以内。径迹探测器仅测量π介子束产生的高传能线密度(LET)成分;正是这些成分在负π介子治疗方案中特别受关注。塑料径迹探测器似乎具有许多用于π介子剂量测定的有利特性。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验