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豚鼠精囊内β-肾上腺素能受体的存在。

The presence of -adrenoceptors in the guinea-pig seminal vesicle.

作者信息

Spedding M, Weetman D F

出版信息

Br J Pharmacol. 1972 May;45(1):21-8. doi: 10.1111/j.1476-5381.1972.tb09572.x.

DOI:10.1111/j.1476-5381.1972.tb09572.x
PMID:4402824
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1666210/
Abstract
  1. The preparation of longitudinal smooth muscle strips from guinea-pig seminal vesicles is described.2. Isoprenaline and salbutamol inhibited contractions produced by parasympathomimetic agents.3. The inhibitory action of isoprenaline was blocked by low concentrations of propranolol and butoxamine. It was concluded that beta(2)-adrenoceptors were present in the tissue.4. The inhibitory action of isoprenaline was not apparent when adrenaline, noradrenaline, hypogastric nerve or transmural stimulation were used to contract the tissue.
摘要
  1. 描述了从豚鼠精囊制备纵向平滑肌条的方法。

  2. 异丙肾上腺素和沙丁胺醇抑制拟副交感神经药引起的收缩。

  3. 低浓度的普萘洛尔和丁氧胺可阻断异丙肾上腺素的抑制作用。由此得出结论,该组织中存在β(2) -肾上腺素能受体。

  4. 当使用肾上腺素、去甲肾上腺素、腹下神经或跨壁刺激使组织收缩时,异丙肾上腺素的抑制作用不明显。

相似文献

1
The presence of -adrenoceptors in the guinea-pig seminal vesicle.豚鼠精囊内β-肾上腺素能受体的存在。
Br J Pharmacol. 1972 May;45(1):21-8. doi: 10.1111/j.1476-5381.1972.tb09572.x.
2
The effects of adrenaline, noradrenaline and isoprenaline on inhibitory alpha- and beta-adrenoceptors in the longitudinal muscle of the guinea-pig ileum.肾上腺素、去甲肾上腺素和异丙肾上腺素对豚鼠回肠纵肌中抑制性α和β肾上腺素能受体的作用。
Br J Pharmacol. 1970 Jun;39(2):398-413. doi: 10.1111/j.1476-5381.1970.tb12903.x.
3
An evidence for the presence of beta-receptors in the seminal vesicle of guinea-pig.豚鼠精囊存在β受体的证据。
Indian J Med Res. 1973 Feb;61(2):260-3.
4
The effect of butoxamine, N-isopropylmethoxamine and salbutamol (AH-3365) on melanophore beta-adrenergic receptors.丁氧胺、N-异丙基甲氧胺和沙丁胺醇(AH-3365)对黑素细胞β-肾上腺素能受体的作用。
J Pharm Pharmacol. 1969 Dec;21(12):854-5. doi: 10.1111/j.2042-7158.1969.tb08185.x.
5
Steric aspects of adrenergic drugs. XVI. Beta adrenergic receptors of guinea-pig atria and trachea.肾上腺素能药物的空间因素。十六。豚鼠心房和气管的β肾上腺素能受体。
J Pharmacol Exp Ther. 1971 Mar;176(3):634-49.
6
Adrenergic beta receptors in seminal vesicle.精囊中的肾上腺素能β受体。
Indian J Exp Biol. 1974 Nov;12(6):577-8.
7
The occurrence of postsynaptic alpha- and beta-adrenoceptors in the guinea-pig gall bladder.豚鼠胆囊中突触后α和β肾上腺素能受体的存在情况。
Br J Pharmacol. 1980;71(1):185-9. doi: 10.1111/j.1476-5381.1980.tb10924.x.
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Distribution and types of adrenoceptors in the guinea-pig ileum: the action of alpha- and beta-adrenoceptor blocking agents.豚鼠回肠中肾上腺素能受体的分布及类型:α和β肾上腺素能受体阻断剂的作用
Br J Pharmacol. 1982 Aug;76(4):569-78. doi: 10.1111/j.1476-5381.1982.tb09256.x.
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Antagonism by beta-adrenoceptor blocking agents of the antianaphylactic effect of isoprenaline.β-肾上腺素能受体阻断剂对异丙肾上腺素抗过敏作用的拮抗作用。
Br J Pharmacol. 1971 Aug;42(4):620-30. doi: 10.1111/j.1476-5381.1971.tb07146.x.
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The reversal of phenoxybenzamine-produced alpha-adrenoceptor blockade by the isomers of propranolol and INPEA.
J Pharm Pharmacol. 1971 May;23(5):332-8. doi: 10.1111/j.2042-7158.1971.tb09923.x.

引用本文的文献

1
Effects of metoclopramide and isoprenaline in the rat vas deferens; interactions with alpha-adrenoceptors.胃复安和异丙肾上腺素对大鼠输精管的作用;与α-肾上腺素能受体的相互作用。
Br J Pharmacol. 1980;71(1):113-20. doi: 10.1111/j.1476-5381.1980.tb10916.x.
2
Distribution of alpha- and beta-adrenoceptors in human urinary bladder.α-和β-肾上腺素能受体在人膀胱中的分布
Br J Pharmacol. 1974 Apr;50(4):525-9. doi: 10.1111/j.1476-5381.1974.tb08585.x.
3
Proceedings: A theoretical model of two functionally opposite receptor populations.论文集:两种功能相反的受体群体的理论模型。
Br J Pharmacol. 1975 Oct;55(2):311P.
4
The pharmacology of adrenergic neuronal responses in the cerebral cortex: evidence for excitatory alpha- and inhibitory beta-receptors.大脑皮质中肾上腺素能神经元反应的药理学:兴奋性α受体和抑制性β受体的证据。
Br J Pharmacol. 1977 Apr;59(4):635-41. doi: 10.1111/j.1476-5381.1977.tb07732.x.

本文引用的文献

1
PERIPHERALLY LOCATED ADRENERGIC NEURONS INNERVATING THE VAS DEFERENS AND THE SEMINAL VESICLE OF THE GUINEA-PIG.支配豚鼠输精管和精囊的外周肾上腺素能神经元。
Experientia. 1965 Feb 15;21:98-100. doi: 10.1007/BF02144766.
2
SYMPATHETIC BETA-RECEPTORS AND THE GUINEA-PIG VAS DEFERENS.交感β受体与豚鼠输精管
Br J Pharmacol Chemother. 1965 Feb;24(1):194-204. doi: 10.1111/j.1476-5381.1965.tb02095.x.
3
A COMPARISON OF THE CARDIAC STIMULATING AND BRONCHODILATOR ACTIONS OF SELECTED SYMPATHOMIMETIC AMINES.某些拟交感神经胺的心脏刺激作用与支气管扩张作用的比较
Proc Soc Exp Biol Med. 1964 Jun;116:331-3. doi: 10.3181/00379727-116-29239.
4
SOME ACTIONS OF CATECHOLAMINES ON THE SMOOTH MUSCLE OF THE GUINEA-PIG VAS DEFERENS.儿茶酚胺对豚鼠输精管平滑肌的某些作用。
Aust J Exp Biol Med Sci. 1964 Feb;42:40-53. doi: 10.1038/icb.1964.4.
5
PREGANGLIONIC AND POSTGANGLIONIC STIMULATION OF THE GUINEA-PIG ISOLATED VAS DEFERENS PREPARATION.豚鼠离体输精管标本的节前和节后刺激
Br J Pharmacol Chemother. 1963 Dec;21(3):569-80. doi: 10.1111/j.1476-5381.1963.tb02024.x.
6
THE RESPONSE OF ISOLATED STRIPS OF CAT SPLEEN TO SYMPATHOMIMETIC DRUGS AND THEIR ANTAGONISTS.猫脾脏离体组织条对拟交感神经药物及其拮抗剂的反应。
J Pharmacol Exp Ther. 1963 Oct;142:99-110.
7
THE EFFECTS OF GANGLION-BLOCKING AND POSTGANGLIONIC SYMPATHOLYTIC DRUGS ON PREPARATIONS OF THE GUINEA-PIG VAS DEFERENS.神经节阻断药和节后交感神经阻滞药对豚鼠输精管标本的作用
Br J Pharmacol Chemother. 1963 Aug;21(1):190-201. doi: 10.1111/j.1476-5381.1963.tb01515.x.
8
Observations on the isolated vas deferens.对离体输精管的观察
Br J Pharmacol Chemother. 1963 Apr;20(2):299-306. doi: 10.1111/j.1476-5381.1963.tb01469.x.
9
The relation of circulating noradrenaline to the effect of sympathetic stimulation.循环去甲肾上腺素与交感神经刺激效应的关系。
J Physiol. 1960 Feb;150(2):295-305. doi: 10.1113/jphysiol.1960.sp006388.
10
The effect on the isolated rabbit heart of vagal stimulation and its modification by cocaine, hexamethonium and ouabain.迷走神经刺激对离体兔心脏的影响以及可卡因、六甲铵和哇巴因对其的影响。
J Physiol. 1956 Mar 28;131(3):678-89. doi: 10.1113/jphysiol.1956.sp005493.