Some studies and comments on hepatic and extrahepatic microsomal toxication-detoxication systems. A limited discussion of some of the heterogeneities of these systems and of their responses to stimulation of enzyme "induction".
作者信息
Fouts J R
出版信息
Environ Health Perspect. 1972 Oct;2:55-66. doi: 10.1289/ehp.720255.
Abstract
摘要
相似文献
1
Some studies and comments on hepatic and extrahepatic microsomal toxication-detoxication systems. A limited discussion of some of the heterogeneities of these systems and of their responses to stimulation of enzyme "induction".关于肝脏和肝外微粒体中毒-解毒系统的一些研究及评论。对这些系统的一些异质性及其对酶“诱导”刺激的反应进行有限的讨论。
Environ Health Perspect. 1972 Oct;2:55-66. doi: 10.1289/ehp.720255.
2
Stimulation of hepatic microsomal drug-metabolizing enzymes in mice by 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) and 3,4-benzpyrene.
Toxicol Appl Pharmacol. 1973 May;25(1):60-70. doi: 10.1016/0041-008x(73)90163-4.
3
Comparison of microsomal drug hydroxylation in lung and liver of various species.不同物种肺和肝脏中微粒体药物羟基化作用的比较。
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Some selected studies on hepatic microsomal drug-metabolizing enzymes--environment interactions.
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Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1968;260(2):189-90.
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Reaction of drugs with microsomal liver hydroxylase: its influence on drug action.药物与肝微粒体羟化酶的反应：其对药物作用的影响。
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[On the question of inducibility of microsomal enzymes for the example of coumarin hydroxylation in the rabbit liver].[以兔肝中香豆素羟基化为例探讨微粒体酶的诱导性问题]
J Bacteriol. 1968 Apr;95(4):568-74.
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Selenium and hepatic microsomal hemoproteins.硒与肝微粒体血红素蛋白
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The isolated perfused lung.离体灌注肺。
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Perinatal development of conjugative enzyme systems.结合酶系统的围产期发育。
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Metabolic activation/deactivation reactions during perinatal development.围产期发育过程中的代谢激活/失活反应。
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Effects of PBBs on cattle. III. Target organ modification as shown by renal function and liver biochemistry.多溴联苯对牛的影响。III. 肾功能和肝脏生化指标显示的靶器官改变。
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本文引用的文献
1
HEPATIC DRUG METABOLISM DURING THE PERINATAL PERIOD.围产期的肝脏药物代谢
Ann N Y Acad Sci. 1965 Mar 12;123:245-51. doi: 10.1111/j.1749-6632.1965.tb12263.x.
2
FURTHER STUDIES ON THE STIMULATION OF HEPATIC MICROSOMAL DRUG METABOLIZING ENZYMES BY DDT AND ITS ANALOGS.滴滴涕及其类似物对肝微粒体药物代谢酶的刺激作用的进一步研究
Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1965 Jan 8;249:486-500. doi: 10.1007/BF00246555.
3
Stimulation of hepatic microsomal drug metabolism in the newborn and fetal rabbit.新生和胎儿兔肝脏微粒体药物代谢的刺激作用
J Pharmacol Exp Ther. 1962 Jul;137:103-6.
4
The metabolism of drugs by subfractions of hepatic microsomes.药物在肝微粒体亚组分中的代谢。
Biochem Biophys Res Commun. 1961 Dec 20;6:373-8. doi: 10.1016/0006-291x(61)90148-6.
5
Drug metabolism in the newborn rabbit.新生兔的药物代谢
Science. 1959 Apr 3;129(3353):897-8. doi: 10.1126/science.129.3353.897.
6
The influence of DDT and gamma-chlordane on the metabolism of hexobarbital and zoxazolamine in 2 mouse strains.滴滴涕和γ-氯丹对两种小鼠品系中己巴比妥和唑沙氯铵代谢的影响。
Biochem Pharmacol. 1967 Jun;16(6):1001-6. doi: 10.1016/0006-2952(67)90272-9.
7
Effect of pretreatment of rabbits with phenobarbital or 3-methylcholanthrene on the distribution of drug-metabolizing enzyme activity in subfractions of hepatic microsomes.
J Pharmacol Exp Ther. 1967 Aug;157(2):435-45.
8
Further studies on the metabolism of drugs by subfractions of hepatic microsomes.肝脏微粒体亚组分对药物代谢的进一步研究。
J Pharmacol Exp Ther. 1967 Mar;155(3):479-93.
9
The metabolism of drugs by hepatic microsomal enzymes. Studies on intramicrosomal distribution of enzymes and relationships between enzyme activity and structure of the hepatic endoplasmic reticulum.
Exp Mol Pathol. 1966 Oct;5(5):475-90. doi: 10.1016/0014-4800(66)90027-x.
10
Influence of 3,4-benzpyrene or gamma-chlordane on the rate of metabolism and acute toxicity of aminopyrine, hexobarbital, and zoxazolamine in the mouse.
Toxicol Appl Pharmacol. 1968 Sep;13(2):212-9. doi: 10.1016/0041-008x(68)90095-1.
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