Boyd K R
Infect Immun. 1972 Jun;5(6):933-7. doi: 10.1128/iai.5.6.933-937.1972.
The antigenic relationships among Hart Park (HP) virus strain AR 70, Flanders virus strain 61-7484, and other related strains were investigated. Strains AR 70 and 61-7484 were shown to be antigenically related but different from each other in neutralization, complement fixation, and double-diffusion tests. Two strains isolated in Texas and one strain each, isolated in Illinois and Florida, appeared to be closely related if not identical to Flanders virus (61-7484) and antigenically related but different from HP virus AR 70. Ten additional strains isolated in 10 different states were compared to the two prototype strains. Seven of the 10 could not be distinguished from Flanders virus, and all 10 strains were different from HP virus. The results indicate that a virus-type consisting of viruses antigenically related if not identical to Flanders virus is widely distributed within the United States, whereas HP virus is antigenically related but different from this type.
对哈特帕克(HP)病毒AR 70株、佛兰德斯病毒61 - 7484株及其他相关毒株之间的抗原关系进行了研究。结果显示,AR 70株和61 - 7484株在抗原上相关,但在中和试验、补体结合试验和双向扩散试验中彼此不同。在得克萨斯州分离出的两株病毒以及分别在伊利诺伊州和佛罗里达州分离出的各一株病毒,即便与佛兰德斯病毒(61 - 7484)不完全相同,似乎也与之密切相关,且在抗原上与HP病毒AR 70株相关但不同。将在10个不同州分离出的另外10株病毒与这两株原型毒株进行了比较。10株中的7株无法与佛兰德斯病毒区分开来,且所有10株病毒均与HP病毒不同。结果表明,一种由即便与佛兰德斯病毒不完全相同但在抗原上相关的病毒组成的病毒类型在美国广泛分布,而HP病毒在抗原上与之相关但属于不同类型。