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口蹄疫病毒毒株鉴别中一些免疫学方法的比较

A comparison of some immunological methods for the differentiation of strains of foot-and-mouth disease virus.

作者信息

Forman A J

出版信息

J Hyg (Lond). 1975 Apr;74(2):215-25. doi: 10.1017/s002217240002427x.

Abstract

Two FMDV strains which had been previously differentiated by complement-fixation were compared by guinea-pig protection test, kinetic neutralization and micro-neutralization tests. It was found that these tests, which have not been previously applied by the methods described, were all capable of FMDV strain differentiation. Similar differences were found by all methods, which suggests that comparisons made by cross-CF, cross-neutralization or cross-protection involve measurement of the same antigen/antibody interactions.

摘要

通过豚鼠保护试验、动态中和试验和微量中和试验,对两种先前通过补体结合试验区分的口蹄疫病毒株进行了比较。结果发现,这些先前未按所述方法应用的试验均能够区分口蹄疫病毒株。所有方法均发现了类似的差异,这表明通过交叉补体结合试验、交叉中和试验或交叉保护试验进行的比较涉及对相同抗原/抗体相互作用的测量。

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