Stewart D A, Moghadam H
Can Med Assoc J. 1972 Dec 9;107(11):1082-4.
Much confusion exists about the necessity of using antibiotic drugs to treat upper respiratory tract infections in children, especially infants. In this study the frequency of bacterial causes of such infections was studied in 4746 children under three years of age. Clinical evidence of infection was absent in half of these children and present in the others. There was no practical difference between the frequency of positive cultures from infected and non-infected children, suggesting that antibiotics were not required.
对于使用抗生素治疗儿童尤其是婴幼儿上呼吸道感染的必要性,存在很多困惑。在本研究中,对4746名三岁以下儿童此类感染的细菌病因发生率进行了研究。这些儿童中有一半没有感染的临床证据,另一半有感染证据。感染儿童和未感染儿童的培养阳性率没有实际差异,这表明不需要使用抗生素。