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[促胰液素和胰酶泌素试验期间收集的胰十二指肠液脱落细胞学研究在胰腺癌诊断中的价值与局限性]

[Value and limitations of exfoliative cytological study of the pancreatico-duodenal juice collected during the secretin and pancreozymin test in the diagnosis of pancreatic carcinoma].

作者信息

Farini R, Del Favero G, Matarazzo R, Rebuffi A, Costantin G, Fabris G, Pedrazzoli S, Adorati M, Madia D, Kind R, Naccarato R

出版信息

Minerva Med. 1979 Jan 31;70(5):369-74.

PMID:440613
Abstract

Studies on exfoliative cytology of the pancreatic-duodenal juice in the diagnosis of pancreas neoplasia are not numerous and the data reported are not uniform. The present study examines 176 patients, 18 of them suffering from carcinoma of the pancreas. In these latter patients there were no advanced signs of the disease. Cytology gave a correctly negative result in 46.8% of the normal subjects and in those with non-neoplastic pancreatic or digestive conditions, correctly positive in 66.6% of the pancreas neoplasias, falsely negative in 2,2% of the total series and in 33.3% of the pancreatic cancers, and falsely positive in 1,1% of the series. In 47.7% of cases, the study proved useless owing to the absence of material in the collected juice.

摘要

关于胰十二指肠液脱落细胞学检查在胰腺肿瘤诊断中的研究并不多,且所报道的数据也不一致。本研究对176例患者进行了检查,其中18例患有胰腺癌。在这些胰腺癌患者中,并无该疾病的晚期体征。细胞学检查在46.8%的正常受试者以及患有非肿瘤性胰腺或消化系统疾病的患者中得出正确的阴性结果,在66.6%的胰腺肿瘤中得出正确的阳性结果,在整个系列中2.2%以及胰腺癌患者中33.3%的病例中得出假阴性结果,在该系列中1.1%的病例中得出假阳性结果。在47.7%的病例中,由于收集的液体中没有样本,该研究被证明毫无用处。

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