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卵巢中肾样癌。一项临床病理、组织化学及电子显微镜研究。

Mesonephroid carcinoma of the ovary. A clinicopathologic, histochemical, and electron microscopic study.

作者信息

Klemi P J, Grönroos M

出版信息

Obstet Gynecol. 1979 Apr;53(4):472-9.

PMID:440650
Abstract

Eighteen patients with mesonephroid ovarian carcinoma were investigated. Typical findings for the mesonephroid tumors were abundant extracellular an some intracellular neutral mucin mixed with sulfate and carboxyl groups, and large amounts of glycogen, especially in clear cells. The latter observation is considered to be an important aid in distinguishing them from other epithelial ovarian carcinomas. Some cells contained intracellular cysts that were covered with stubby microvilli similar to those found on the lumenal surfaces of the larger cysts in the tumors. Simultaneous estrogenic endometrial activity in the post-menopausal patients was frequently observed. The significance of this observation is discussed.

摘要

对18例中肾样型卵巢癌患者进行了研究。中肾样肿瘤的典型表现为细胞外和一些细胞内有丰富的中性黏液,混有硫酸根和羧基基团,以及大量糖原,尤其是在透明细胞中。后一观察结果被认为是将它们与其他上皮性卵巢癌区分开来的重要依据。一些细胞含有细胞内囊肿,其表面覆盖着短粗的微绒毛,类似于肿瘤中较大囊肿腔表面的微绒毛。绝经后患者常同时出现雌激素作用下的子宫内膜活动。讨论了这一观察结果的意义。

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Obstet Gynecol. 1979 Apr;53(4):472-9.
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Ultrastructure of clear cell carcinoma of the ovary. Case report and review of the literature.
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