Klemi P J, Grönroos M
Obstet Gynecol. 1979 May;53(5):572-9.
A material consisting of 23 endometrioid ovarian carcinomas, including 2 rare endometrioid tumors with argyrophil cells, was analyzed clinically and with the use of various histochemical staining methods. Electron microscopy was performed in 3 cases. Apical neutral mucin mixed with sulfate and carboxyl groups was typical for the cells at the light microscopic level, and a prominent Golgi complex with many small secretory vesicles was commonly seen at the ultrastructural level. The nuclei had concentric nuclear bodies and nucleoli with mesh-basket appearance. There was a positive correlation between the grade of differentiation and clinical stage. The corrected 5-year survival rate was 80% in stage I, 50% in stage II, 17% in stage III, and 0% in stage IV; the overall 5-year survival rate was 46%. Signs of increased endometrial estrogen activity were found in 6 of the 12 postmenopausal patients. In the whole series, 6 endometrial carcinomas were found simultaneously with the ovarian carcinoma.
对由23例子宫内膜样卵巢癌组成的材料进行了临床分析，并使用了各种组织化学染色方法，其中包括2例罕见的含嗜银细胞的子宫内膜样肿瘤。对3例进行了电子显微镜检查。在光学显微镜下，顶端中性黏液混合有硫酸根和羧基是这些细胞的典型特征，在超微结构水平上通常可见一个突出的高尔基体，伴有许多小分泌泡。细胞核有同心核体和呈网篮状外观的核仁。分化程度与临床分期之间存在正相关。I期的校正5年生存率为80%，II期为50%，III期为17%，IV期为0%；总体5年生存率为46%。在12例绝经后患者中，有6例发现子宫内膜雌激素活性增加的迹象。在整个系列中，有6例子宫内膜癌与卵巢癌同时发现。
