Gorodeski I G, Paz M, Insler V, Fishel J
Obstet Gynecol. 1979 May;53(5):611-6.
A new method is presented for differentiating amniotic fluid from cervical mucus, based on differences in the respective carbohydrate concentrations present in these fluids. Glucose and fructose are present in high concentrations in cervical mucus during pregnancy, average values being 240 and 30.4 mg/100 ml, respectively. Their concentrations in amniotic fluid, however, are low, averaging 39 and 3.3 mg/ml, respectively. Examination of 215 women between 36 and 42 weeks' gestation, using either glucose or fructose values, revealed a high degree of discrimination between amniotic fluid and cervical mucus. The best results, however, were obtained by employing the calculated linear sum 3.32 log glucose plus log fructose for each sample. Inaccuracy rates were low in comparison to those of other diagnostic methods, such as pH values, ferning, and Nile blue sulfate staining. A further advantage of the method is that it remains fairly accurate even when the time interval between rupture of the membranes and the investigation exceeds 24 hours.
本文提出了一种基于羊水和宫颈黏液中碳水化合物浓度差异来区分二者的新方法。孕期宫颈黏液中葡萄糖和果糖浓度较高，平均值分别为240和30.4毫克/100毫升。然而，它们在羊水中的浓度较低，平均分别为39和3.3毫克/毫升。对215名妊娠36至42周的女性进行检测，无论是使用葡萄糖还是果糖值，都显示出羊水和宫颈黏液之间有高度的区分度。不过，通过对每个样本采用计算得出的线性和（3.32×葡萄糖对数+果糖对数）可获得最佳结果。与其他诊断方法（如pH值、羊齿状结晶和尼罗蓝硫酸盐染色）相比，该方法的错误率较低。该方法的另一个优点是，即使胎膜破裂与检查之间的时间间隔超过24小时，它仍相当准确。
