Gregoriou O, Pitoulis S, Coutifaris B, Varonos D, Batrinos M
Obstet Gynecol. 1979 May;53(5):630-2.
To test the hypothesis that prolactin (PRL) plays a role in the hormonal events of labor, serum PRL levels in 15 normal secundigravidas were measured on 2 occasions 10-15 days before delivery, at the onset of labor, at cervical dilatation of 5 and 10 cm, at the time of delivery, and on the first, second, and fifth days postpartum. The mean level of PRL was 163 ng/ml +/- 26 ng/ml at the onset of cervical dilatation; it typically decreased with the progress of labor, reaching a value of 140 ng/ml +/- 21 ng/ml at the time of delivery. The differences during the various stages of labor, however, were not found to be statistically significant. Postpartum values were significantly lower (P less than 0.01) on the fifth day after parturition. It is therefore unlikely that PRL is involved in or influenced by the hormonal interplay that occurs during labor.
为验证催乳素（PRL）在分娩激素变化过程中起作用这一假说，对15例正常经产妇在分娩前10 - 15天、临产前、宫颈扩张5厘米和10厘米时、分娩时以及产后第1天、第2天和第5天进行了两次血清PRL水平测定。宫颈扩张开始时PRL平均水平为163纳克/毫升±26纳克/毫升；通常随着产程进展而降低，分娩时降至140纳克/毫升±21纳克/毫升。然而，分娩各阶段的差异未发现具有统计学意义。产后第5天的值显著较低（P＜0.01）。因此，PRL不太可能参与分娩期间发生的激素相互作用或受其影响。
