二乙氨基乙基葡聚糖、聚凝胺、葡聚糖和硫酸葡聚糖对AKR小鼠自发性白血病发生及BALB - c小鼠病毒诱导白血病的影响。
Influence of DEAE-dextran, polybrene, dextran and dextran sulphate on spontaneous leukaemia development in AKR mice and virus induced leukaemia in BALB-c mice.
作者信息
Ebbesen P
出版信息
Br J Cancer. 1974 Jul;30(1):68-72. doi: 10.1038/bjc.1974.114.
Abstract
AKR mice of which more than 90% die of lymphatic thymus leukaemia, had their mean survival time increased by weekly intraperitoneal inoculation of either of the two polycations DEAE-dextran and polybrene. Administration of the neutral dextran had no effect, whereas the polyanion dextran sulphate accelerated leukaemia development.Adult BALB/c mice infected with Rauscher leukaemia virus and treated from the time of palpable spleen enlargement, showed a life prolonging effect of the polycations DEAE/dextran and polybrene, and of neutral dextran. BALB/c mice treated from the time of leukaemia infection, however, showed a life prolonging effect with polyanion dextran sulphate and also of neutral dextran.
摘要
超过90%的AKR小鼠死于胸腺淋巴细胞白血病，通过每周腹腔注射两种聚阳离子（二乙氨基乙基葡聚糖和聚凝胺）中的任何一种，其平均存活时间得以延长。给予中性葡聚糖没有效果，而聚阴离子硫酸葡聚糖加速了白血病的发展。感染劳舍尔白血病病毒的成年BALB/c小鼠，从脾脏可触及肿大时开始治疗，结果显示聚阳离子二乙氨基乙基葡聚糖/葡聚糖和聚凝胺以及中性葡聚糖具有延长寿命的作用。然而，从白血病感染时开始治疗的BALB/c小鼠，聚阴离子硫酸葡聚糖以及中性葡聚糖均显示出延长寿命的作用。
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本文引用的文献
1
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Nature. 1956 Mar 24;177(4508):576-7. doi: 10.1038/177576a0.
2
Normal and pathologic anatomy of the reticular tissue in laboratory mice, with a classification and discussion of neoplasms.实验室小鼠网状组织的正常与病理解剖学，以及肿瘤的分类与讨论。
J Natl Cancer Inst. 1954 Jun;14(6):1281-433.
3
Cell electrophoretic mobilities in Friend virus disease.弗瑞德病毒病中的细胞电泳迁移率
Nature. 1967 Jul 15;215(5098):279-80. doi: 10.1038/215279a0.
4
A quantitative investigation of the G (Gross) antigen in preleukemic and leukemic cells.对白血病前期细胞和白血病细胞中G（总）抗原的定量研究。
Exp Cell Res. 1966 May;42(2):230-42. doi: 10.1016/0014-4827(66)90286-2.
5
The effect of neuraminidase on the fate of transfused lymphocytes.神经氨酸酶对输注淋巴细胞命运的影响。
J Exp Med. 1969 Mar 1;129(3):551-67. doi: 10.1084/jem.129.3.551.
6
7
Inhibitory effect of polycations on the transplantability of mouse leukaemia reversed by heparin.多阳离子对小鼠白血病移植性的抑制作用被肝素逆转。
Eur J Cancer (1965). 1968 May;4(2):157-62. doi: 10.1016/0014-2964(68)90013-3.
8
Oncogenic water-soluble polycations. 1. Induction of sarcomas in mice by diethylaminoethyl-dextran.
J Natl Cancer Inst. 1973 Feb;50(2):387-401. doi: 10.1093/jnci/50.2.387.
9
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Science. 1972 Dec 1;178(4064):1001-2. doi: 10.1126/science.178.4064.1001.
10
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