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1
Influence of DEAE-dextran, polybrene, dextran and dextran sulphate on spontaneous leukaemia development in AKR mice and virus induced leukaemia in BALB-c mice.二乙氨基乙基葡聚糖、聚凝胺、葡聚糖和硫酸葡聚糖对AKR小鼠自发性白血病发生及BALB - c小鼠病毒诱导白血病的影响。
Br J Cancer. 1974 Jul;30(1):68-72. doi: 10.1038/bjc.1974.114.
2
Chalone-like effect abrogated by dextran sulphate and heparin polyanion pretreatment of target cells.硫酸葡聚糖和肝素多阴离子预处理靶细胞可消除类抑素样效应。
Br J Cancer. 1975 Jun;31(6):649-52. doi: 10.1038/bjc.1975.111.
3
Effect of tissue specific mitotic inhibitors on survival time of spontaneous and virus-induced murine leukaemia and influence on myocardial degeneration.组织特异性有丝分裂抑制剂对自发和病毒诱导的小鼠白血病存活时间的影响以及对心肌变性的影响。
Scand J Haematol. 1978 Aug;21(2):131-8. doi: 10.1111/j.1600-0609.1978.tb02503.x.
4
Life span, leukaemia and amyloid incidences of untreated and polycation-treated AKR mice.未治疗和经聚阳离子处理的AKR小鼠的寿命、白血病发病率和淀粉样蛋白发病率。
Br J Cancer. 1978 Jan;37(1):76-80. doi: 10.1038/bjc.1978.11.
5
DEAE-dextran enhancement of in vivo infection with murine leukemia virus.二乙氨基乙基葡聚糖增强小鼠白血病病毒的体内感染
Arch Gesamte Virusforsch. 1973;40(3):307-10. doi: 10.1007/BF01242550.
6
Modes of cell death in Rauscher leukaemia virus infection.劳舍尔白血病病毒感染中的细胞死亡模式。
Pathology. 1974 Oct;6(4):315-22. doi: 10.3109/00313027409077341.
7
The induction of myeloid leukaemias by Rauscher murine leukaemia virus.劳氏肉瘤病毒诱导小鼠髓系白血病
J Gen Virol. 1985 Apr;66 ( Pt 4):909-13. doi: 10.1099/0022-1317-66-4-909.
8
Preferential localization of gallium-67 citrate in tissues of leukemic mice.柠檬酸镓-67在白血病小鼠组织中的优先定位。
J Natl Cancer Inst. 1970 Mar;44(3):695-700.
9
Effect of polycations on growth and dissemination of the encephalomyocarditis virus in mice.聚阳离子对小鼠脑心肌炎病毒生长和传播的影响。
J Virol. 1967 Oct;1(5):988-95. doi: 10.1128/JVI.1.5.988-995.1967.
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The enhancing effect of sodium nitrite on virus-induced leukemia in mice.亚硝酸钠对小鼠病毒诱导白血病的增强作用。
Cancer Detect Prev. 1997;21(4):312-8.

引用本文的文献

1
Mechanism of the anti-tumour effect of glucans and fructosans: a comparison with C. parvum.葡聚糖和果聚糖的抗肿瘤作用机制：与微小隐孢子虫的比较。
Br J Cancer. 1977 Jul;36(1):41-8. doi: 10.1038/bjc.1977.152.
2
Life span, leukaemia and amyloid incidences of untreated and polycation-treated AKR mice.未治疗和经聚阳离子处理的AKR小鼠的寿命、白血病发病率和淀粉样蛋白发病率。
Br J Cancer. 1978 Jan;37(1):76-80. doi: 10.1038/bjc.1978.11.
3
Chalone-like effect abrogated by dextran sulphate and heparin polyanion pretreatment of target cells.硫酸葡聚糖和肝素多阴离子预处理靶细胞可消除类抑素样效应。
Br J Cancer. 1975 Jun;31(6):649-52. doi: 10.1038/bjc.1975.111.

本文引用的文献

1
Differences between the electrical charge carried by normal and homologous tumour cells.正常细胞与同源肿瘤细胞所携带电荷的差异。
Nature. 1956 Mar 24;177(4508):576-7. doi: 10.1038/177576a0.
2
Normal and pathologic anatomy of the reticular tissue in laboratory mice, with a classification and discussion of neoplasms.实验室小鼠网状组织的正常与病理解剖学，以及肿瘤的分类与讨论。
J Natl Cancer Inst. 1954 Jun;14(6):1281-433.
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Cell electrophoretic mobilities in Friend virus disease.弗瑞德病毒病中的细胞电泳迁移率
Nature. 1967 Jul 15;215(5098):279-80. doi: 10.1038/215279a0.
4
A quantitative investigation of the G (Gross) antigen in preleukemic and leukemic cells.对白血病前期细胞和白血病细胞中G（总）抗原的定量研究。
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The effect of neuraminidase on the fate of transfused lymphocytes.神经氨酸酶对输注淋巴细胞命运的影响。
J Exp Med. 1969 Mar 1;129(3):551-67. doi: 10.1084/jem.129.3.551.
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Effect of DEAE-dextran on interferon production and protective effect in mice treated with the double-stranded polynucleotide complex polyinosinic-polycytidylic acid.
J Immunol. 1969 Jan;102(1):24-7.
7
Inhibitory effect of polycations on the transplantability of mouse leukaemia reversed by heparin.多阳离子对小鼠白血病移植性的抑制作用被肝素逆转。
Eur J Cancer (1965). 1968 May;4(2):157-62. doi: 10.1016/0014-2964(68)90013-3.
8
Oncogenic water-soluble polycations. 1. Induction of sarcomas in mice by diethylaminoethyl-dextran.
J Natl Cancer Inst. 1973 Feb;50(2):387-401. doi: 10.1093/jnci/50.2.387.
9
Thymus-dependent and thymus-independent lymphocyte separation: relation to exposed sialic acid on cell surface.胸腺依赖性和非胸腺依赖性淋巴细胞分离：与细胞表面暴露的唾液酸的关系。
Science. 1972 Dec 1;178(4064):1001-2. doi: 10.1126/science.178.4064.1001.
10
Thymus and bone marrow derived lymphatic leukaemia in mice.小鼠胸腺和骨髓源性淋巴白血病
Nature. 1973 Feb 9;241(5389):396-8. doi: 10.1038/241396a0.

二乙氨基乙基葡聚糖、聚凝胺、葡聚糖和硫酸葡聚糖对AKR小鼠自发性白血病发生及BALB - c小鼠病毒诱导白血病的影响。

Influence of DEAE-dextran, polybrene, dextran and dextran sulphate on spontaneous leukaemia development in AKR mice and virus induced leukaemia in BALB-c mice.

作者信息

Ebbesen P

出版信息

Br J Cancer. 1974 Jul;30(1):68-72. doi: 10.1038/bjc.1974.114.

DOI:10.1038/bjc.1974.114
PMID:4413876
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2009190/
Abstract

AKR mice of which more than 90% die of lymphatic thymus leukaemia, had their mean survival time increased by weekly intraperitoneal inoculation of either of the two polycations DEAE-dextran and polybrene. Administration of the neutral dextran had no effect, whereas the polyanion dextran sulphate accelerated leukaemia development.Adult BALB/c mice infected with Rauscher leukaemia virus and treated from the time of palpable spleen enlargement, showed a life prolonging effect of the polycations DEAE/dextran and polybrene, and of neutral dextran. BALB/c mice treated from the time of leukaemia infection, however, showed a life prolonging effect with polyanion dextran sulphate and also of neutral dextran.

摘要

超过90%的AKR小鼠死于胸腺淋巴细胞白血病，通过每周腹腔注射两种聚阳离子（二乙氨基乙基葡聚糖和聚凝胺）中的任何一种，其平均存活时间得以延长。给予中性葡聚糖没有效果，而聚阴离子硫酸葡聚糖加速了白血病的发展。感染劳舍尔白血病病毒的成年BALB/c小鼠，从脾脏可触及肿大时开始治疗，结果显示聚阳离子二乙氨基乙基葡聚糖/葡聚糖和聚凝胺以及中性葡聚糖具有延长寿命的作用。然而，从白血病感染时开始治疗的BALB/c小鼠，聚阴离子硫酸葡聚糖以及中性葡聚糖均显示出延长寿命的作用。